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Pharyngitis clinical trials

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NCT ID: NCT03720301 Recruiting - Pharyngitis Clinical Trials

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

Start date: October 17, 2018
Phase: N/A
Study type: Interventional

Post-operative sore throat (POST) ranks as the 8th most undesirable effect in the post-operative period and is noted by up to 90% of patients receiving an endotracheal tube. [1-3] This study aims to show that a simple 5 minute preoperative and intraoperative osteopathic medical manipulation protocol can decrease the severity and or the incidence of post-operative sore throat thereby decreasing morbidity and increasing patient satisfaction and return to daily life.

NCT ID: NCT03391700 Recruiting - Sore Throat Clinical Trials

Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

Investigators assess and compare postoperative sore throat and hoarseness in the group maintaining moderate relaxation and deep relaxation during operation.

NCT ID: NCT03369132 Recruiting - Sore Throat Clinical Trials

Efficacy of Natural Seawater Based Throat Spray in Acute Sore Throat Relief

FLASH
Start date: November 6, 2017
Phase: N/A
Study type: Interventional

Prospective, randomized, double-blind, placebo-controlled, multicentre clinical trial to assess the efficacy and tolerability of natural seawater based throat spray among adult patients with acute sore throat.

NCT ID: NCT03264911 Recruiting - Clinical trials for Group A Streptococcal Pharyngitis

Group A Pharyngitis in Children: The GASPARD Study

GASPARD
Start date: January 27, 2017
Phase: Phase 4
Study type: Interventional

Evaluate the necessity to treat with antibiotics GAS pharyngitis in children in Switzerland. The null hypothesis is that antibiotic treatment is not necessary for GAS pharyngitis in this population.

NCT ID: NCT03222700 Recruiting - Postoperative Pain Clinical Trials

The Recovery Profiles After Robotic or Open Thyroidectomy

Start date: September 1, 2016
Phase: N/A
Study type: Observational

In the present study, The investigators investigated the effect of surgical methods on the recovery of patients after robotic surgery and open thyroidectomy

NCT ID: NCT03031808 Recruiting - Clinical trials for Intubation Complication

Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant on Sore Throat and Hemodynamics

Start date: October 31, 2017
Phase: Phase 4
Study type: Interventional

When a surgical procedure is performed under general anesthesia, the Airways are often secured With an endotracheal tube. Some patients experience sore throat thereafter. Studies have shown a reduction of these side effects when by use of muscle relaxants or a lidocain spray prior to the intubation. At Ostfold Hospital Trust, the investigators use one of the two methods or nothing. These methods will be studied systematically. Heart rate and blood pressure rise during the intubation procedure. The investigators will also study the differences between the groups.

NCT ID: NCT02775994 Recruiting - Periodic Fever Clinical Trials

Ilaris (Canakinumab) in Patient With Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA)

Start date: August 2016
Phase: Phase 1
Study type: Interventional

Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis (PFAPA) is one of the most common, least explored periodic fever syndrome in childhood. This study aims to investigate whether a single dose of an interleukin beta (IL-1) antagonist, Canakinumab will be able to abort PFAPA flares in patients who experience a flare in an average of 2 weeks or less. This will be a single arm open label pilot study. 10 patients will be recruited from 1 center (Pediatric rheumatology unit -Schneider children's medical center of Israel). Patients in ages 2-10 years old who are diagnosed with PFAPA according to clinical criteria at least 3 months prior to enrollment and who are under regular care for this disease (single dose of glucocorticoids during flare) and who suffer from more than 4 PFAPA flares for the last 2 months, will be screened for this study. In the second documented flare, patients will be enrolled to receive a single dose of subcutaneous (SC) Canakinumab 4 mg/kg. The primary outcome is defined as - 50% reduction in PFAPA flares for the next 2 consecutive months as reported by the patient (use of diary) and documented by the patient primary care physician and/ or the researcher in a monthly follow up visits. Secondary outcome measure are define as time to flare (days) and Parent/patient quality of life assessment measured by 100mm visual analog scale (VAS).

NCT ID: NCT01841866 Recruiting - Clinical trials for Post Operative Sore Throat After LMA Removal

Laryngeal Mask Airway Removal During Deep Anesthesia in Children

Start date: May 2013
Phase: N/A
Study type: Interventional

Laryngeal mask airway (LMA) is widely used in children.The appropriate time to remove laryngeal mask airway is still inconclusive.Sore throat is one of common complications after general anesthesia. Sometimes postoperative sore throat affects patients' satisfaction and daily activities. It can be correlated with dysphagia and may limit oral intake especially in children.The incidence of postoperative sore throat after laryngeal mask airway insertion varies from 5.8-34% in adult(13) and 17.5% in pediatric.Somehow, almost the studies of postoperative sore throat after laryngeal mask airway removal were done in awake state. Our study object to test that post operative sore throat after LMA removal in deep anesthetized children is lower than awake children.

NCT ID: NCT01838993 Recruiting - Sore Throat Clinical Trials

Inhalation of Lidocaine Before Intubation

Start date: January 2013
Phase: N/A
Study type: Interventional

We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.

NCT ID: NCT01681667 Recruiting - Pharyngitis Clinical Trials

Tablet vs. Liquid Suspension Ibuprofen in the Relief of Pain

Start date: September 2013
Phase: Phase 4
Study type: Interventional

Ibuprofen (also known as Advil or Motrin) is a medication that is known to reduce pain. It is also known that ibuprofen levels in the blood rise higher and faster if the medication is taken in liquid suspension. This study will attempt to determine if ibuprofen suspended in a liquid works to relieve sore throat pain faster than pills of ibuprofen. It will also determine whether patients with sore throat prefer to take pill or liquid form of the medication.