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Pharmacotherapy clinical trials

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NCT ID: NCT04861727 Completed - Pharmaceutical Care Clinical Trials

Use of Technology to Optimize Hypertension Treatment in Elderly People in Primary Care

MINOR
Start date: June 6, 2021
Phase: N/A
Study type: Interventional

The control of blood pressure (BP) in the elderly is influenced by several factors, among them, the measurement methodology. The measurement of BP in the office is prone to failures, so the use of technology associated with blood pressure measurements at home is an alternative to minimize failures and contribute to the optimization of treatment. The objective of this study will be to evaluate the adequacy of the treatment of Systemic Arterial Hypertension (SAH) in primary care using Home Blood Pressure Monitoring (MRPA). Method: Randomized clinical trial with hypertensive patients, aged 60 years or over, attended at the Family Pharmacy service inserted in the primary care of the municipal health network. The subjects who accept to participate in the study will be randomized to the intervention / control groups. submitted to MRPA, will undergo analysis of the pharmacotherapy prescribed for the treatment of SAH, collection of clinical data, which together will support the assessment of the adequacy of the treatment of hypertension. When inadequacies in pharmacotherapy are identified, suggestions for changes will be forwarded to the prescriber / professional or assistant health team, weighted by the pharmacist in agreement with the patient and according to the guidelines of the Brazilian Guideline on Hypertension. The outcomes: changes in treatment and blood pressure control in the intervention and control groups will be evaluated.

NCT ID: NCT04687566 Recruiting - Clinical trials for Amphetamine Addiction

Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction

Start date: August 11, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators will conducted a randomized double-blind placebo-controlled study to investigate the treatment outcomes of add-on low dose dextromethorphan (DM), memantine (MM), or dextromethorphan and memantine combination (DM+MM) in amphetamine-type stimulants use disorder patients.

NCT ID: NCT04245566 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Prostatic Artery Embolization vs. Pharmacotherapy for LUTS/BPH

EMPATHY
Start date: September 2021
Phase: Phase 3
Study type: Interventional

This study compares safety and efficacy of prostatic artery embolization and pharmacotherapy in the treatment of lower urinary tract symptoms associated wit benign prostatic hyperplasia.

NCT ID: NCT03485417 Recruiting - Clinical trials for Schizophrenia and Related Disorders

Substance Misuse To Psychosis for Stimulants

Start date: June 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

In Hong Kong, less than 5% of stimulants abusers were reported to misuse these substances via injection. Also, it is well known that patients with co-morbid substance abuse/dependence and psychosis or schizophrenia-related disorders are prone to earlier treatment discontinuation and high oral medication non-adherence, resulting in poorer overall outcomes. With the recent availabilities of the 4-weekly long-acting injectable form of aripiprazole, and the 4-weekly and the 3-monthly long-acting injectable form of paliperidone palmitate, on the background of the surging phenomenon of stimulant misuses in Hong Kong, it is a timely opportunity to conduct an early pharmacotherapy intervention study to offer an evidence-based strategy aiming to stop individuals with substance use disorders with psychosis to develop into a more chronic disabling dependence or co-morbid state.

NCT ID: NCT03485274 Completed - Depression Clinical Trials

Substance Misuse To Psychiatric Disorders for Cannabis

Start date: July 25, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

With the recent availability of vortioxetine, and the surging phenomenon of cannabis misuses amongst young abusers, it is a timely opportunity to conduct an early pharmacotherapy intervention study to offer an evidence-based strategy aiming to stop individuals with cannabis use disorders with depressive or anxiety symptoms, to develop into a more chronic disabling dependence or co-morbid state.