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Pharmacokinetics of Mirabegron clinical trials

View clinical trials related to Pharmacokinetics of Mirabegron.

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NCT ID: NCT04641975 Terminated - Clinical trials for Overactive Bladder (OAB)

A Study to Evaluate Mirabegron in Pediatric Participants From 5 to Less Than 18 Years of Age With Overactive Bladder (OAB)

Dolphin
Start date: March 15, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy of mirabegron in children (5 to < 12 years of age) with OAB. This study will also evaluated the safety and tolerability of mirabegron in pediatric participants with OAB and evaluated the pharmacokinetics after multiple dose administration of mirabegron in pediatric participants with OAB.

NCT ID: NCT04501640 Completed - Food Effect Clinical Trials

A Study to Investigate the Effect of Food With Mirabegron in Healthy Chinese Participants

Start date: September 21, 2020
Phase: Phase 4
Study type: Interventional

This study determined the effect of food on the pharmacokinetics (PK) of single oral doses of mirabegron in healthy Chinese male and female participants. This study also evaluated the safety and tolerability of single oral doses of mirabegron in healthy Chinese male and female participants.

NCT ID: NCT02211846 Completed - Overactive Bladder Clinical Trials

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Mirabegron OCAS (Oral Controlled Absorption System) in Pediatric Subjects With Neurogenic Detrusor Overactivity or Overactive Bladder

Start date: September 21, 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics as well as the safety and tolerability of mirabegron OCAS tablets after single-dose administration at different dose levels in children and adolescents with NDO or OAB.

NCT ID: NCT01478568 Completed - Healthy Subjects Clinical Trials

To Evaluate the Effect of Mirabegron (YM178) on Blood Levels of Desipramine When They Are Taken Together

Start date: October 2008
Phase: Phase 1
Study type: Interventional

The study aims to evaluate if blood levels of desipramine change whilst being dosed at the same time with daily mirabegron.

NCT ID: NCT01478529 Completed - Healthy Subjects Clinical Trials

A Study to Find Out How Much Mirabegron Gets Into the Body After Dosing With a Tablet Formulation

Start date: February 2006
Phase: Phase 1
Study type: Interventional

A study to evaluate how much of the active compound of mirabegron comes into the blood circulation when given as a controlled-release pill as compared to given intravenously.

NCT ID: NCT01478490 Completed - Healthy Subjects Clinical Trials

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Start date: September 2002
Phase: Phase 1
Study type: Interventional

The study aims to compare blood and urine concentrations of mirabegron (YM178) in healthy poor or extensive metabolizers for CYP2D6 and to evaluate if blood levels of metoprolol change whilst being dosed at the same time with daily miragebron.

NCT ID: NCT01297192 Completed - Healthy Volunteers Clinical Trials

A Clinical Study to Assess the Effect on Pharmacokinetics of Dosing Mirabegron (YM178) and Solifenacin Simultaneously

Start date: March 2009
Phase: Phase 1
Study type: Interventional

This study investigates whether mirabegron (YM178) has an effect on the pharmacokinetics of solifenacin and whether solifenacin has an effect on the pharmacokinetics of mirabegron.

NCT ID: NCT01297179 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate the Possible Effects of Taking Mirabegron While Taking a Contraceptive Pill

Start date: October 2008
Phase: Phase 1
Study type: Interventional

The objective of this study is to determine the effect of multiple doses of mirabegron on the pharmacokinetics of an oral contraceptive.

NCT ID: NCT01285596 Completed - Healthy Volunteers Clinical Trials

A Study to Evaluate How Mirabegron Enters and Leaves the Bloodstream According to Age and Sex

Start date: March 2009
Phase: Phase 1
Study type: Interventional

Young and elderly, male and female subjects are each given 2 different doses of mirabegron for 7 days each. Levels of mirabegron in the blood are assessed.

NCT ID: NCT00940121 Completed - Healthy Clinical Trials

Pharmacokinetics of Oral Mirabegron With Different Release Rates Versus Intravenous (IV) Mirabegron

Start date: April 30, 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmacokinetics of three doses of oral mirabegron formulations with three different release rates versus three doses of mirabegron administered intravenously; to study safety and side effects of the oral and IV doses of mirabegron.