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Phacoemulsification clinical trials

View clinical trials related to Phacoemulsification.

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NCT ID: NCT05529485 Completed - Cataract Clinical Trials

Quantification of Factors Influencing Endothelial Damage During Phacoemulsification

PREDICSPILOT
Start date: January 12, 2022
Phase:
Study type: Observational

The aim of this study is to determine the principal factors that influence endothelial cell loss three month post cataract surgery. Methods: Multi center observational Cohort study, inclusion period from 12/01/2022 to 10/06/2022. One hundred and seventy-five eyes of hundred and four patients who have appointment for cataract surgical indication were included. The percentage of corneal endothelial cell loss was quantified using specular microscopy before and 3 months after the surgery. 14 variables (pre-operative and intra-operative) that could be associated to endothelial cell injury were selected. A bivariate analysis of relationship between these factors and endothelial cell loss at 3 months was performed by simple linear regression (Wilcoxon and Fischer tests). Multivariate analysis was performed by multiple linear regression in order to identify the factors independently related to endothelial cell loss.

NCT ID: NCT04702802 Completed - Clinical trials for Age-related Cataract

Clinical Study to Evaluate the Safety of the Viscoelastic Substance PRO-149 When Used During Phacoemulsification, Compared to Healon® EndoCoat.

PRO-149
Start date: September 7, 2021
Phase: Phase 1
Study type: Interventional

Pilot, controlled, parallel group, open, randomized clinical trial to evaluate the safety of the viscoelastic substance PRO-149 (sodium hyaluronate 3%) after trans-surgical administration as a device in performing phacoemulsification and intraocular lens implantation in 36 patients with age-related cataract, compared to Healon® EndoCoat (sodium hyaluronate 3%).

NCT ID: NCT03972670 Completed - Cataract Clinical Trials

Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery

ECOCHI
Start date: August 1, 2014
Phase:
Study type: Observational

To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.

NCT ID: NCT03587909 Completed - Cataract Surgery Clinical Trials

FLACS vs Phaco in Shallow Anterior Chamber

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Phacoemulsification in eyes with a shallow anterior chamber (ACD < 2.2mm) presents with problems of safe access to the cataract and increased vulnerability of the endothelium and a higher tendency of complications such as descemet's detachment and iris prolapse. A shallow anterior chamber is also responsible for the high incidence of glaucoma and postoperative complications after cataract surgery. Femtosecond assisted cataract surgery has made cataract surgery safer and more predictable. The effective phacoemulsification time and intra-operative manipulation is greatly reduced in FLACS. However phacoemulsification still remains the most widely performed cataract surgery around the world. Post-operative outcomes after phacoemulsification in patients having shallow anterior chamber have been extensively reported in literature over the years. There is no head to head comparison in terms of intraoperative performance and post-operative outcomes between FLACS and phacoemulsification in eyes with shallow anterior chamber. The aim is to compare the intra-operative performance and post-operative outcomes in eyes undergoing femtosecond laser assisted cataract surgery versus eyes undergoing phacoemulsification in eyes having shallow anterior chamber. The study will bring an understanding on the question: Do patients undergoing Femtosecond laser assisted cataract surgery behave differently from those undergoing phacoemulsification?

NCT ID: NCT03364972 Completed - Clinical trials for Patient Satisfaction

A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00

Start date: February 6, 2018
Phase: N/A
Study type: Interventional

This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal, aspheric, hydrophobic acrylic intraocular lenses (IOLs). A new product is compared with an established one.

NCT ID: NCT03054103 Completed - Cataract Clinical Trials

Sedation Methods During Cataract Surgery

Start date: May 3, 2016
Phase: Phase 4
Study type: Interventional

Background: Phacoemulsification is the most common surgical procedure performed in the United States and European Union and sedation is commonly used during phacoemulsification to help alleviate patient anxiety and prevent the patient from interfering with the procedure. The investigators have administered ketamine in addition to midazolam in this regard. To study the effectiveness of this technique, The investigators proposed a study to determine if adding low-dose ketamine to midazolam has any beneficial (or negative) effects on operating conditions, patient satisfaction, and recovery during and after unilateral phacoemulsification procedures performed using topical anesthesia and intravenous (IV) conscious sedation. Methods: In a free-standing Outpatient Surgery Center, the investigators conducted a randomized, double-masked, 3-arm, prospective comparison of IV midazolam only vs. midazolam with ketamine 5 mg IV vs. midazolam with ketamine 10 mg IV. The investigators then measured a single surgeon's assessment of surgical conditions, self-reported patient satisfaction, postoperative pain score, and duration of postoperative stay. The investigators also analyzed the dose of midazolam required to meet subjective anxiolysis in each group.

NCT ID: NCT03031652 Completed - Phacoemulsification Clinical Trials

Clinical Analysis of Ocular Parameters Contributing to Intraoperative Pain During Standard Phacoemulsification

Start date: March 1, 2016
Phase: N/A
Study type: Observational

Charts of 142 patients who underwent standard phacoemulsification under topical anesthesia between March and August 2016 were reviewed. The pain during phacoemulsification and 1 h after surgery was assessed and compared using a visual analog scale.

NCT ID: NCT01381783 Completed - Phacoemulsification Clinical Trials

Phacoemulsification Under Topical Anesthesia and Its Complications

Start date: January 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if topical anesthesia is safe for phacoemulsification in eyes with comorbidities.

NCT ID: NCT01247155 Completed - Complications Clinical Trials

First Postoperative Day Review After Uneventful Phacoemulsification

Start date: n/a
Phase: N/A
Study type: Observational

The purpose of this randomized trial was to examine the value of the review on the first postoperative day after uneventful phacoemulsification cataract surgery.

NCT ID: NCT01146964 Completed - Cataract Clinical Trials

Comparison of Manual Super Small Incision Cataract Surgery and Phacoemulsification

Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of manual super small incision cataract surgery (MSSICS) and Phacoemulsification.