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Clinical Trial Summary

The incidence and mortality of hematological malignancies remain high. Although 18F-FDG PET/CT imaging is the most common molecular imaging technique used in clinic, the non-specific uptake of 18F-FDG leads to the problems of false negative or positive in hematological malignancies, which makes it difficult to diagnose and evaluate the efficacy. CXCR4 (C-X-C Chemokine Receptor Type 4) is overexpressed in various hematological malignancies, and is associated with poor prognosis. CXCR4-targeted molecular imaging, such as 68Ga-pentixafor PET/CT imaging, has an important potential in hematological malignancies. Therefore, this study will evaluate the efficacy of CXCR4-targeted PET/CT imaging for diagnosis and staging of hematological malignancies, compared with 18F-FDG PET/CT imaging.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05255926
Study type Interventional
Source Zhongnan Hospital
Contact Yong He, MD, PhD
Phone +86-27-67812698
Email vincentheyong@163.com
Status Recruiting
Phase N/A
Start date March 1, 2022
Completion date March 31, 2024

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