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Personality Disorder; Unstable clinical trials

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NCT ID: NCT04259554 Completed - Depression Clinical Trials

OFC rTMS in Emotionally Unstable and Depressed Patients

ORIENT
Start date: February 14, 2020
Phase: N/A
Study type: Interventional

Treatment of depression with conventional transcranial magnetic stimulation (rTMS) has shown high evidence using high-frequency left dorsolateral prefrontal cortex (DLPFC) stimulation. Recently, it could be demonstrated that treatment of the right orbitofrontal cortex may be effective in patients who did not respond to conventional DLPFC rTMS. Orbitofrontal cortex (OFC) seem to be involved in the etiopathology of emotionally instable personality disorders. Thus, the present one-arm trial is a pilot study investigating if OFC rTMS is feasable, tolerable and effective.