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Catheter Ablation and Surgical Ablation of Persistent Atrial Fibrillation With Severe Atrial Fibrosis

Persistent Atrial Fibrillation Clinical Trial

Official title:
A Randomized Control Study of Catheter Ablation Versus Surgical Ablation as a Treatment in Patients With Persistent Atrial Fibrillation With Severe Atrial Fibrosis: a Chinese Registry Study.

Clinical Trial Summary

This is an open label, randomized parallel control clinical trial evaluating the efficacy and safety of catheter ablation and surgical ablation in patients with persistent atrial fibrillation with severe atrial fibrosis.

Clinical Trial Description

This is an open label, randomized parallel control clinical trial. Patients with persistent atrial fibrillation with severe atrial fibrosis are 1:1:1 randomized into the group A (circumferential pulmonary vein isolation + linear ablation + bi-atrial mapping + driver ablation), group B (circumferential pulmonary vein isolation + linear ablation + vein of Marshall ethanol infusion) and group C (surgical ablation). Postoperative recurrence rate and other indicators are analyzed to evaluate the efficacy and safety of catheter ablation and surgical ablation in patients with persistent atrial fibrillation with severe atrial fibrosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05153486
Study type Interventional
Source Shanghai Chest Hospital
Contact Mu Qin, M.D.
Phone +8613052320103
Email qinmuae@163.com
Status Not yet recruiting
Phase N/A
Start date December 1, 2021
Completion date November 30, 2024
View Details
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