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Epicardial Mini-Maze Versus Catheter Ablation for the Management of Persistent Atrial Fibrillation — EMMCAF  

Persistent Atrial Fibrillation Clinical Trial

Official title:
Epicardial Mini-Maze Versus Catheter Ablation for the Management of Persistent Atrial Fibrillation

Clinical Trial Summary

This study will assess the efficacy of catheter ablation versus the Wolf Mini-Maze surgical ablation for rhythm control in patients with persistent afib.

Clinical Trial Description

Higher success rates have been achieved after a single surgical ablation when compared to catheter ablation, however contiguous and transmural lesions are not always guaranteed.

Even though, catheter ablation is now being offered for symptomatic persistent AF, recurrence after the index procedure in such a persistent AF substrate is not unusual. Redo-catheter ablation is routinely offered for such patients; however long term success still remains low. Non-pulmonary vein triggers are often targeted in such redo-catheter ablation procedures; though this approach remains controversial. More recently, the Wolf Mini-Maze procedure has been utilized with promising results.

This study proposes to randomize a group of persistent AF patients to undergo either catheter ablation or the surgical mini-maze procedure with left atrial appendage (LAA) ligation ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03446222
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact
Status Withdrawn
Phase N/A
Start date June 2016
Completion date December 18, 2018
View Details
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