Peritonitis Clinical Trial
— BCAEOfficial title:
The BCAE Study: Best Care for Abdominal Emergencies
Verified date | September 2020 |
Source | Portsmouth Hospitals NHS Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This is a single-centre retrospective cohort study utilising electronic hospital records.
The aim of this study is to improve care for all patients with an intestinal emergency,
irrespective of whether they have surgery or not. Data will be derived from electronic
patient records collected as part of routine clinical patient care on all general adult wards
(excluding maternity) between 2013 and 2020. We will then identify patients who had an
emergency laparotomy, and those who had a laparoscopic procedure. We aim to identify 2
further groups where treatment is non-surgical (but could be medical or interventional
radiology) or where treatment is considered futile, suggesting that an early focus on end of
life care might be appropriate. The primary objective is to provide mortality rates for
different treatment options, and analysis of short- and long-term outcomes. The secondary
endpoints are to define patient sub-groups with similar health characteristics based on
clinical data and an established risk index and to use statistical analysis to predict the
risk of death for each patient group and treatment option, which will allow us to identify
the best care pathways for each cluster.
Status | Not yet recruiting |
Enrollment | 2500 |
Est. completion date | March 30, 2022 |
Est. primary completion date | December 1, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 16 Years and older |
Eligibility |
Inclusion Criteria: All acute general surgical adult patients admitted between 2013 and 2020 with all of the conditions below: - Must have an acute intestinal condition, based on their ICD-10 codes and OPSC-4 codes - Must be >= 16 years of age at the time of admission - Have at least one full set of vital signs recorded on the day of admission - Have at least one full set of routine blood tests recorded on the day of admission Exclusion Criteria: - Maternity admissions during/after pregnancy - Patients admitted or undergoing abdominal surgery for a second time or more |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Portsmouth Hospitals University NHS Trust | Portsmouth | Hampshire |
Lead Sponsor | Collaborator |
---|---|
Simon Toh | University of Portsmouth |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mortality rates of different interventions | Provide mortality rates for different treatment options, and analysis of short- and long-term outcomes. | 2013-2020 | |
Secondary | Define patient sub-groups with similar health characteristics | Define patient sub-groups with similar health characteristics based on clinical data and an established risk index. option, which will allow us to identify the best care pathways for each cluster. |
2013-2020 | |
Secondary | Predict the risk of death for each patient group | Use statistical analysis to predict the risk of death for each patient group and treatment option, which will allow us to identify the best care pathways for each cluster. | 2013-2020 |
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