Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial

Peripheral Diabetic Neuropathy Clinical Trial

Official title:

Effects of Moderate Physical Activity on Early Symptoms of Peripheral Diabetic Neuropathy in Type-II Diabetes: A Randomized Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05491850
• Other study ID #: RIPHAH/FR&AHS/Letter-0985
• Status: Completed
• Phase: N/A
• Start date: October 1, 2021
• Est. completion date: December 25, 2021

Study information

• Verified date: August 2022
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study determines the effects of moderate physical activity on early symptoms of peripheral diabetic neuropathy in type-II diabetes. Most of the literature shows the impact of physical activity to manage/controlling diabetes. Some studies were conducted on animals to study the impact of physical activity on diabetic neuropathy and neurogenesis. There is no study on the impact of physical activity to manage early symptoms of peripheral diabetic neuropathy in patients with type-II diabetes in humans. This study finds the impact of moderate physical activity to manage early symptoms of peripheral diabetic neuropathy in patients with type-II diabetes in humans.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 17
• Est. completion date: December 25, 2021
• Est. primary completion date: November 30, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 35 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients with Type-II Diabetes
• Diagnosed cases of Peripheral Diabetic Neuropathy
• Peripheral Diabetic Neuropathy Stage 1 & 2
• Numbness or reduced ability to feel pain or temperature changes.
• Tingling or burning sensation.
• Sharp pains or cramps.
• Increased sensitivity to touch
• Males and females
• Age: 35-65
• HbA1c above 6.5
• Mild activity level on IPAQ-7 (< 150min/per week)
• Berg Balance Scale score (< 45)

Exclusion Criteria:

• Cardiac Issues
• Any neurological issue
• Lower limb deformity
• Acute injury
• Hip and Knee OA
• Patients with walking difficulty
• Diabetic foot

Related Conditions & MeSH terms

• Diabetes Mellitus, Type 2
• Diabetic Neuropathies
• Peripheral Diabetic Neuropathy
• Peripheral Nervous System Diseases

Intervention

Other:
• Moderate Physical Activity for Peripheral Diabetic Neuropathy
Moderate physical activity can increase movement and heart rate are particularly important for people suffering with peripheral neuropathy. Physical activity can improve blood circulation, which strengthens nerve tissues by increasing the flow of oxygen.

Locations

Country	Name	City	State
Pakistan	RHS Rehabilitation Center	Islamabad	Federal

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Effect of moderate physical activity on early symptoms of peripheral diabetic neuropathy in type-II diabetes	Research Hypothesis	2 Months