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Non-invasive Computer-Aided Phenotyping of Vasculopathy — Q-CAMP  

Peripheral Arterial Disease Clinical Trial

Official title:
vascuCAP: Non-invasive Computer-Aided Phenotyping of Vasculopathy

Clinical Trial Summary

The investigators use MRI and/or CT to evaluate the extent, as well as, the structure, composition, and functional aspects of atherosclerotic plaques in human carotid and femoral arteries in patients scheduled to undergo an endarterectomy of the aforementioned vascular beds as part of their routine clinical care.

Clinical Trial Description

The investigators hypothesize that in vivo MRI and/or CT examinations of patients, when suitably acquired and analyzed with the vascuCAP™ analysis software, can provide a sufficiently accurate profile of plaque characteristics to provide an objective basis for patient management. Study subjects include patients undergoing endarterectomies to mitigate their clinical risk or symptoms for conditions including stroke, claudication, and critical limb ischemia. The endarterectomy specimens removed at surgery will allow a direct comparison between the MRI information obtained prior to the surgery and the histopathological analyses of the arterial specimens. The vascuCAP™ measurements of structural and functional features of the arterial wall will be performed in patients undergoing endarterectomy. Measured results will be compared in a blinded fashion with histology to assess performance of plaque profiling and build a pilot prediction model for risk scoring. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02143102
Study type Observational
Source Elucid Bioimaging Inc.
Contact
Status Completed
Phase
Start date July 2014
Completion date June 30, 2017
View Details
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