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NCT05682833 Clinical Trial

Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis

Periodontitis Clinical Trial

Official title:
Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis: A Split Mouth Randomized Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05682833
Other study ID # REC-22-02-26-S
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date October 1, 2022
Est. completion date June 20, 2024

Study information
Verified date January 2023
Source University of Sharjah
Contact Prof. Zahi Badran Prof.
Phone +97165057353
Email zbadran@sharjah.ac.ae
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

General Objective : To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning Specific Objective : To determine the effect of intra-pocket application of hyaluronic acid /chlorohexidine gel in non surgical periodontal treatment on clinical periodontal parameters and microbiological level .

Recruitment information / eligibility
Status Recruiting
Enrollment 20
Est. completion date June 20, 2024
Est. primary completion date December 20, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 60 Years
Eligibility Inclusion Criteria: - Age : 20-60 years old - At least 20 remaining teeth - Periodontitis stage III and IV ,Grade A, B and C Exclusion Criteria: - Patients taking specific medications: antibiotic , anticoagulants or anti-inflammatory - Previous periodontal therapy in the past 3-6 months. - Immunocompromised patients - Systemically diseased patients: Diabetes ,osteoporosis etc - History of allergies or hypersensitivity reactions to chlorohexidine or Hyaluronic acid - Pregnant or lactating women. - Heavy Smokers (more than 20/day)

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Non surgical periodontal therapy
Subgingival ultrasonic debridement + manual root planning

Locations
Country Name City State
United Arab Emirates University Dental Hospital Sharjah Sharjah

Sponsors (1)
Lead Sponsor Collaborator
University of Sharjah

Country where clinical trial is conducted

United Arab Emirates, 

Outcome
Type Measure Description Time frame Safety issue
Primary pocket depth 2 months
Primary Bleeding on Probing 2 months
Primary Clinical attachment level 2 months
Secondary Plaque index 2 months
See also
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