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Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis Treatment

Periodontitis Clinical Trial

Official title:
Syringeable Atorvastatin Loaded Eugenol Enriched PEGylated Cubosomes In-situ Gel for the Intra-pocket Treatment of Periodontitis: Statistical Optimization and Clinical Assessment

Clinical Trial Summary

Periodontitis is a destructive chronic inflammatory disease characterized by periodontium damage and pocket formation between the tooth and the gingival margin resulting in ultimate tooth loss. Various topical anti-inflammatory drugs were used to treat inflammation in periodontitis. Introducing atorvastatin as a novel remedy for periodontitis treatment necessitates developing a syringeable modified delivery system capable of targeting inflammation within the periodontal pockets.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05583643
Study type Interventional
Source Misr University for Science and Technology
Contact
Status Completed
Phase Phase 1
Start date December 7, 2021
Completion date June 30, 2022
View Details
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