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Nitazoxanide as a New Local Adjunctive to Nonsurgical Treatment of Moderate Periodontitis

Periodontitis Clinical Trial

Official title:
Nitazoxanide as a New Local Adjunctive to Nonsurgical Treatment of Moderate Periodontitis: Clinical and Biochemical Evaluation

Clinical Trial Summary

The aim of the study was to assess the effect of nitazoxanide delivered subgingivally as thermosensitive hydrogel on the clinical and biochemical outcomes of SRP in patients with moderate periodontitis.

Clinical Trial Description

A randomized, controlled clinical trial in a split-mouth design was conducted on forty patients equally divided between two groups: a control group treated with full mouth scaling and root planing (SRP) and a test group treated with SRP combined with subgingivally delivered 0.01% NTZ sustained release Poloxamer 407/hyaluronic acid thermosensitive hydrogel. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04768530
Study type Interventional
Source Alexandria University
Contact
Status Completed
Phase Phase 2
Start date July 20, 2019
Completion date April 30, 2020
View Details
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