Supportive Periodontal Therapy Under Antiresorptive Therapy

Periodontitis Clinical Trial

Official title:

Supportive Periodontal Therapy Under Antiresorptive Therapy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04192188
• Other study ID #: S-630/2019
• Status: Completed
• Start date: December 6, 2019
• Est. completion date: December 30, 2021

Study information

• Verified date: October 2022
• Source: Heidelberg University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This observational study investigates the one-point in time and course of clinical periodontal and dental parameters during supportive periodontal therapy in patients under and without antiresorptive medication.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: December 30, 2021
• Est. primary completion date: February 28, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients undergoing supportive periodontal therapy (SPT) after completing anti-infectious therapy (AIT) in the Section of Periodontology, Clinic of Conservative Dentistry, University Hospital Heidelberg
• Regular attendance to SPT (no interruption of interval of more than one year)
• Existing radiographs (orthopantomogram or dental status) of up to six months before AIT
• ART-group: patients on antiresorptive medication (underlying diseases: osteoporosis, cancer diseases)
• Understanding of participation in this study and given informed consent

Exclusion Criteria:

• Patients < 18 years
• Patients who underwent radiation therapy
• Pregnancy

Related Conditions & MeSH terms

• Antiresorptive Drugs
• Periodontitis

Locations

Country	Name	City	State
Germany	University Hospital Heidelberg	Heidelberg	Baden-Württemberg

Sponsors (1)

Lead Sponsor	Collaborator
Heidelberg University

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Is there a difference in the clinical attachment level between patients under antiresorptive therapy and without antiresorptive medication?		0 months
Secondary	Is Intraoral digital photography suitable for DMFT and implants assessment?		0 months
Secondary	Is there a difference in the clinical attachmentlevel between baseline and 12 months after the beginning of supportive periodontal therapy in patients under antiresorptive therapy compared to patients without antiresorptive medication?		12 months