Study on the Relationship Between Periodontitis and Renal Disease

Periodontitis Clinical Trial

Official title:

Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02417363
• Other study ID #: ZJUSH2015-1
• Status: Recruiting
• Phase: N/A
• First received: April 10, 2015
• Last updated: April 16, 2015
• Start date: October 2013
• Est. completion date: October 2016

Study information

• Verified date: April 2015
• Source: Zhejiang University
• Contact: Na Zhou
• Phone: 86-571-87217437
• Email: kate0228[@]163.com
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.

Description:

A total of 200 population is recruited, individuals are divided into four groups according to a periodontal examination and a general physical examination: healthy individuals ,periodontitis, renal disease patients with healthy periodontium, and renal disease patients wth peridontitis. Fasting blood samples and gingival crevicular fluid are collected from all individuals, and inflammatory markers are analysed for the four groups.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: October 2016
• Est. primary completion date: August 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 25 Years to 55 Years

Eligibility

Inclusion Criteria:

• all participants were in general good health(except renal disease) and non-smoking

Exclusion Criteria:

• less than 20 teeth in the dentin

• hypertension

• the presence of systemic disease (e.g., diabetes mellitus ,coronary heart disease, liver, or lung disease)

• a history or the symptom of any other acute or chronic infections

• systemic antibiotic treatment within previous 4 weeks

• periodontal treatment within1 month

Study Design

Observational Model: Case-Crossover, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Periodontitis

Locations

Country	Name	City	State
China	Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University	Hangzhou	Zhejiang

Sponsors (1)

Lead Sponsor	Collaborator
Zhejiang University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Inflammatory markers analysis of the four groups	Analysis of inflammatory biomarkers of blood and gingival crevicular fluid samples of the four groups	3 months after sampling	Yes