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NCT00969241 Clinical Trial

The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva

Periodontitis Clinical Trial

Official title:
The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00969241
Other study ID # 920090018-YR.ctil
Secondary ID
Status Recruiting
Phase N/A
First received August 30, 2009
Last updated December 22, 2010
Start date July 2009

Study information
Verified date August 2009
Source The Baruch Padeh Medical Center, Poriya
Contact n/a
Is FDA regulated No
Health authority Israel: Ministry of Health
Study type Observational

Clinical Trial Summary

This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.

Description:

Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of this disease causes destruction of connective tissue and bone. As a result of stimulation by bacterial antigen PMN produces free radicals via respiratory burst as a part of host response to infection.

Free radicals can be defined as molecules or molecular fragments with an unpaired electron which imparts certain characteristics to the free radicals such as reactivity . Reactive free radicals are able to produce chemical modifications and to damage proteins, lipids, carbohydrates and nucleotides in the tissues.

Recruitment information / eligibility
Status Recruiting
Enrollment 30
Est. completion date
Est. primary completion date December 2010
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- older than 18

- no medical problems

Exclusion Criteria:

- medical problems

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Israel department of oral and maxillofacial surgery, Baruch Padeh Medical Center Tieberia, Israel Poria

Sponsors (1)
Lead Sponsor Collaborator
The Baruch Padeh Medical Center, Poriya

Country where clinical trial is conducted

Israel, 

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