Periodontitis Clinical Trial
Official title:
The Effect of Periodontal Treatment on the Level of Free Radicals in the Saliva
This study will examine the relationship between free radicals in the saliva and periodontitis. 30 adults, 15 with periodontitis and 15 as a control group will give a sample of saliva before treatment and after treatment. The investigators will examine the free radicals in both groups.
Periodontal disease is a chronic adult condition. Bacteria implicated in the etiology of
this disease causes destruction of connective tissue and bone. As a result of stimulation by
bacterial antigen PMN produces free radicals via respiratory burst as a part of host
response to infection.
Free radicals can be defined as molecules or molecular fragments with an unpaired electron
which imparts certain characteristics to the free radicals such as reactivity . Reactive
free radicals are able to produce chemical modifications and to damage proteins, lipids,
carbohydrates and nucleotides in the tissues.
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Observational Model: Case Control, Time Perspective: Prospective
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