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Periodontitis clinical trials

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NCT ID: NCT03716154 Completed - Periodontitis Clinical Trials

Clinical Effectiveness of Diode Laser as an Adjunct in the Treatment of Periodontitis

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

a randomized controlled single-blinded study. the hypothesis of this clinical trial is that disjunctive use of diode laser improve the clinical parameters of periodontists , and there are significant difference between the conventional treatment and diode laser as an adjunct

NCT ID: NCT03711942 Completed - Clinical trials for Apical Periodontitis

Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients.

Start date: October 15, 2016
Phase: N/A
Study type: Interventional

Periodontal health may jeopardize the success of endodontic treatment.Intraorifice barrier apart from enhancing probability of success of endodontic treatment may also augment periodontal therapy as intra pulpal infection is known to contribute in worsening of periodontal health by promoting marginal bone loss and pocket formation.This study compared the apical healing in healthy and periodontally compromised teeth and evaluated the effect of intra orifice barrier and base in the healing of apical periodontitis.

NCT ID: NCT03708081 Completed - Pulpitis Clinical Trials

Comparative Evaluation of Different File Systems in Postoperative Pain

Start date: June 1, 2017
Phase:
Study type: Observational [Patient Registry]

Postoperative pain is a frequent complication associated with root canal treatment. The apical extrusion of irrigant and debris, including bacteria and necrotic tissue, may lead to postoperative pain, periapical inflammation, and flare-ups. The instrumentation technique and the file design may affect the amount of debris extrusion. The aim of this study was to evaluate the influence of instrumentation techniques on the incidence and intensity of postoperative pain after single-visit root canal treatment.

NCT ID: NCT03692819 Completed - Clinical trials for Chronic Periodontitis Complex

Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis.

Start date: May 2, 2018
Phase: N/A
Study type: Interventional

Currently, with the increase of bacterial resistance to antibiotics associated with its side effects, it is necessary to find other adjuncts to combat the disease that are an alternative to the use of antibiotics. The use of probiotics has been proposed in the literature as an adjunct therapy for the treatment of periodontal diseases, however, few controlled and randomized clinical studies have been performed. The objective of this double-blind randomized controlled trial will be to evaluate the response of clinical and microbiological periodontal parameters to the comparison of two different adjuvant therapies (antibiotic and probiotic) for the treatment of stages II and III grade B periodontitis.

NCT ID: NCT03690479 Completed - Periodontitis Clinical Trials

The Impact of a Modified Probe Tip Design on Patient Perception of Discomfort on Probing and Clinical Parameters Using the Florida Probe® System

Start date: April 4, 2013
Phase: N/A
Study type: Interventional

Patient perception of pain on periodontal probing using a controlled-force, electronic probe was not significantly affected by the use of a modified (ball-end) probe tip design except for in the maxilla, where a standard straight probe tip appeared to be more comfortable for patients.

NCT ID: NCT03677297 Completed - Adult Periodontitis Clinical Trials

"Efficacy Of 1.2% Rosuvastatin Gel In The Management Of Infrabony Defects"

Start date: January 28, 2016
Phase: Phase 4
Study type: Interventional

Study aims to evaluate clinical and radiographic effectiveness of 1.2% Rosuvastatin gel in the treatment of Infrabony defects in chronic periodontitis patients.

NCT ID: NCT03671408 Completed - Periodontitis Clinical Trials

Levels of High-Sensitivity C-Reactive Protein in Heart Transplant Patients

Start date: April 20, 2016
Phase:
Study type: Observational [Patient Registry]

Objectives: The outcomes of heart transplantation are very favorable but inflammation still plays a critical role in deterioration of chronic transplants. Periodontal diseases are not only limited to supporting structures of the teeth, they also cause systemic inflammation. Based on the importance of inflammation in heart transplant recipients and the association between periodontal disease and systemic inflammation, this study explored whether periodontitis may be a modifier of serum high-sensitivity C-reactive protein (HsCRP) in heart transplant patients.

NCT ID: NCT03670979 Completed - Periodontitis Clinical Trials

Periodontal Osseous Wall Piezosplitting and EDTA Root Surface Etching

Start date: January 5, 2016
Phase: N/A
Study type: Interventional

This study was designed to investigate the use of minimally invasive Piezo knife to harvest vascularized interceptal bone pedicle in treating intrabony defects.

NCT ID: NCT03656484 Completed - Clinical trials for Chronic Periodontitis

New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin

HAMELDENT
Start date: January 15, 2019
Phase: Phase 2
Study type: Interventional

The aim of the present study is to determine whether the association of Melatonin and Hyaluronic Acid to the antimicrobial TM paste (3% Tetracyclin and 3% Metronidazole) for periodontal maintenance therapy can improve the attachment level (AL) and alveolar bone support for moderate chronic periodontitis.

NCT ID: NCT03652558 Completed - Periodontitis Clinical Trials

Effects of Ozone Therapy as an Adjunct to Periodontal Treatment

Start date: January 10, 2017
Phase: N/A
Study type: Interventional

This randomized, placebo controlled, split-mouth clinical study trial evaluates the effects of Ozone therapy on clinical and biochemical parameters. Total of 20 participants completed the study . Periodontal parameters were evaluated at baseline and 3 months following periodontal therapy. All participants were treated non-surgically. Topical gaseous ozone was applied into periodontal pockets. Gingival crevicular fluid pentraxin-3 (PTX-3), interleukin-1β (IL-1β) and high sensitivity C-reactive protein (Hs-CRP) were evaluated.