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Periodontitis clinical trials

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NCT ID: NCT03882138 Completed - Clinical trials for Chronic Periodontitis

Influence of Gingival Biotype on the Outcome of Open Flap Debridement

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The influence of periodontal thickness has been documented in outcome of various periodontal interventions like non surgical periodontal therapy, mucogingival therapy, guided tissue regeneration (GTR), crown lengthening and implant dentistry. There is lack of study showing the influence of gingival biotype on outcome of surgical procedure. The present study is therefore undertaken to evaluate the influence of gingival biotype on the outcome of open flap debridement for treatment of chronic periodontitis.

NCT ID: NCT03880448 Completed - Surgery Clinical Trials

Metronidazole vs Placebo as Adjuncts to Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis

Start date: September 19, 2012
Phase: N/A
Study type: Interventional

The objective of this study is to determine whether the use of a systemic antimicrobial (metronidazole) as an adjunct to periodontal surgery provides additional clinical and microbiological beneficial effects compared to periodontal surgery alone plus a placebo, in patients with non treated periodontitis (stage III and IV) positive to Porphyromonas gingivalis.

NCT ID: NCT03874390 Completed - Clinical trials for Chronic Periodontitis

Effects of Ozone Therapy on Clinical Parameters and Inflammatory Cytokines in Chronic Periodontitis Patients

Start date: October 2014
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate of ozone therapy on both clinical and biochemical effects in periodontally patients.

NCT ID: NCT03851757 Completed - Clinical trials for Periodontitis, Adult

Cleansing Efficacy of Waist-shaped Interdental Brushes.

Waist-shaped
Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The aim of the present randomized and single-blinded cross-over study was to compare the cleansing efficacy of waist-shaped interdental brushes with that of cylindric interdental brushes in interproximal sites.

NCT ID: NCT03839719 Completed - Periodontitis Clinical Trials

OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study.

Start date: January 9, 2019
Phase: N/A
Study type: Interventional

- Periodontal disease- Inflammatory, Multifactorial, and Threshold disease. Periodontal disease is a highly prevalent dental disease, an almost 100% prevalence in developing countries. - Non-surgical periodontal includes scaling and root planing (SRP) an essential part of successful periodontal therapy. - The spread of infection through aerosol and splatter has long been considered one of the main reason for the possible transmission of infectious agents and their ill effects on The Health of patients and Dental Health care Professionals. - Aerosols are generated during Tooth preparation/Rotary instrument/ air abrasion/Air-water syringe, Ultrasonic scaler, and while doing Air polishing. - Studies have also reported an association of these aerosols with Respiratory infections, Ophthalmic and Skin infections, Tuberculosis, and Hepatitis B. current research suggests that having patients use an antimicrobial rinse before treatment may decrease microbial aerosols. - Chlorhexidine mouthwash is regarded as Gold Standard mouthwash but, have many local side effects including have many local side effects including extrinsic tooth and tongue brown staining, taste disturbance, enhanced supragingival calculus formation, less commonly, desquamation of oral mucosa, and even liver damage in rats. - In the emerging era of pharmaceuticals, herbal medicines with their naturally occurring active ingredients offer a gentle and enduring way for the restoration of health by the least harmful method. - Ocimum Sanctum (Tulsi) is known as THE QUEEN OF HERBS effective in reducing plaque accumulation, gingival inflammation, and bleeding & has no side effects as compared to Chlorhexidine. Very few studies which can be counted on fingers have been conducted worldwide in this direction, globally showing their beneficial effects.

NCT ID: NCT03836781 Completed - Clinical trials for Chronic Periodontitis

Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist

Start date: April 10, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

In this study, 40 patients with a history of Mild- Periodontitis who were diagnosed with clinical and radiographic findings showed that all of the periodontal parameters before the treatment, during the treatment period Then, scaling & Root planing and oral hygiene instructions were given to the patients, and after 2 weeks, the patients who received the study were randomly divided into two groups (Balanced Block Randomization) with four blocks according to the visit time. To group A, oral chlorohexidine and to B group, the drug Ketorolac was given. 5 mm of the drugs required every 15 days the areas underwent a gingival wash with an insulin syringe, which lasted for 3 months.

NCT ID: NCT03810560 Completed - Clinical trials for Generalized Chronic Periodontitis

Erbium Chromium: YSGG Laser Effect on Surgical Treatment of Chronic Periodontitis

Start date: December 2016
Phase: N/A
Study type: Interventional

Microbiological and Clinical assessment of Er,Cr:YSGG laser in conjunction to open flap debridement (OFD) in treatment of chronic periodontitis through real time PCR assay for quantification of total bacterial load.

NCT ID: NCT03807596 Completed - Clinical trials for Chronic Periodontitis

Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2

Start date: March 16, 2017
Phase: N/A
Study type: Interventional

The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling & root planing (SRP) in patients with chronic periodontitis & diabetes mellitus type 2.

NCT ID: NCT03803176 Completed - Clinical trials for Chronic Periodontitis

Tissue Plasminogen Activator & Plasminogen Activator Inhibitor Type-1 In Gingival Tissues Of Chronic Periodontitis

Start date: February 12, 2018
Phase:
Study type: Observational [Patient Registry]

Tissue Plasminogen Activator and Plasminogen Activator Inhibitor Type-1 Gene Expression will be evaluated clinically and histopathologically through Hematoxylin and eosin as well as by quantitative reverse transcription polymerase chain reaction in the gingival tissues of chronic periodontitis in an attempt to investigate whether the expression of these proteins could be involved in the disease pathogenesis or not, and to assess as well if their expression will be affected by the applied surgical periodontal treatment.

NCT ID: NCT03786133 Completed - Clinical trials for Type 2 Diabetes Mellitus

Chronic Periodontitis Microbiota in Type 2 Diabetes Mellitus Patients

Start date: June 10, 2016
Phase:
Study type: Observational

This study is a retrospective comparative evaluation of six main periodontal pathogens and total bacterial load in chronic periodontitis patients affected or not by type 2 diabetes mellitus by polymerase chain reaction analysis.