Clinical Trials Logo

Periodontitis, Chronic clinical trials

View clinical trials related to Periodontitis, Chronic.

Filter by:
  • None
  • Page 1

NCT ID: NCT06426069 Not yet recruiting - Inflammation Clinical Trials

Assessment of Masticatory Performance in Periodontitis

Start date: June 2024
Phase:
Study type: Observational

The loss of periodontal attachment contributes to reduced masticatory performance and has a negative impact on general health.This clinical trial aims to assess the status of masticatory performance among patients with stage I, stage II, stage III and stage IV periodontitis, along with those with healthy periodontium.

NCT ID: NCT06058923 Recruiting - Periodontitis Clinical Trials

MIST Versus M-MIST for the Treatment of Intrabony Defects

Start date: August 10, 2023
Phase: N/A
Study type: Interventional

This is a 12-month longitudinal, double-blind, parallel-design randomized controlled clinical trial involving surgical therapeutic intervention (Phase 4). It will include 50 participants aged 21 diagnosed with periodontitis (Stage III/IV, Grade A or B), divided into a Test Group (n=25, Minimally invasive single-flap surgery) and a Control Group (n=25, Minimally invasive double-flap surgery). The objective of this randomized, double-blind clinical study is to compare clinical, radiographic, and patient-centered outcomes between minimally invasive single-flap and double-flap techniques in treating isolated infra-bony defects. Twenty-five patients will be treated using the single-flap approach, and 25 patients will receive the double-flap elevation technique. Clinical parameters (plaque and bleeding scores, probing depth, gingival recession, clinical attachment level, and papillary dimensions), digital measurements (changes in gingival margin and papillary volume), radiographic assessments, and patient-centered outcomes (VAS scale) will be evaluated immediately before surgery, at 6 and 12 months post-procedure, while early healing will be assessed after 1 and 2 weeks following the procedures. Mean values and standard deviations will be calculated for each variable, normal distribution will be tested using the Shapiro-Wilk test, and comparisons will be conducted using Student's t-test and one-way ANOVA. A significance level of 5% will be used for all analyses.

NCT ID: NCT04446897 Completed - Clinical trials for Periodontitis, Chronic

Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction

Start date: August 3, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction

NCT ID: NCT03264118 Completed - Clinical trials for Periodontal Diseases

Effects of Antimicrobial Photodynamic Therapy on Regeneration of Class II Furcation Lesions

Start date: April 2, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.

NCT ID: NCT03262701 Terminated - Clinical trials for Periodontitis, Chronic

Adjunctive Hydrogen Peroxide for Periodontal Therapy

AHP
Start date: April 2, 2018
Phase: Phase 4
Study type: Interventional

There have been many adjunctive treatments for the additional clinical benefits to scaling and root planing (SRP) in the treatment of chronic periodontitis. Topical hydrogen peroxide (HP) delivered in a custom fabricated tray has been shown to improve pocket depth (PD) and inflammation. The purpose of this study is to assess the adjunctive treatment outcome of HP gel in custom tray application in individuals with chronic periodontitis receiving SRP. The purpose of this investigator-initiated study is to evaluate and compare the clinical effects of scaling and root planing (SRP) combined with local delivery of 1.7% hydrogen peroxide (HP) gel in customized trays to that of SRP alone.