The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups

Periodontal Inflammation Clinical Trial

Official title:

The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients (A Randomized Clinical Trial)

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06140394
• Other study ID #: P-ME-23-04
• Status: Recruiting
• Phase: N/A
• Start date: April 29, 2023
• Est. completion date: June 29, 2024

Study information

• Verified date: November 2023
• Source: Faculty of Dental Medicine for Girls
• Contact: Alaa HM Naguib, bachelor's
• Phone: 01004962573
• Email: dr.alaaelbarahmtouchy[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients

Description:

2 ml of unstimulated saliva will be collected using spitting method, the collected samples will then be analyzed using Elisa technique for salivary Inducible nitrous oxide synthase levels.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 44
• Est. completion date: June 29, 2024
• Est. primary completion date: April 29, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years to 90 Years

Eligibility

Inclusion Criteria:

• males and females

• aged below 40 or above 60

• periodontitis stage 2

• no tooth loss due to periodontitis

Exclusion Criteria:

• smoking habits

• history of antibiotics

• history of systemic diseases

Related Conditions & MeSH terms

• Inflammation
• Periodontal Inflammation

Intervention

Other:
• diode laser
low level diode therapy
• non surgical scaling
non surgical scaling using ultrasonic

Locations

Country	Name	City	State
Egypt	Al-Azhar University	Cairo	Nasrcity Nasr Street
Egypt	Hamdy Nassar	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Faculty of Dental Medicine for Girls

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical parameters (gingival index)	measurement if the gingival index using scoring system. A score from 0.1-1.0 = mild inflammation; 1.1-2.0 = moderate inflammation from, and 2.1-3.0 signifies severe inflammation.	6 months
Primary	clinical parameters (clinical attachment loss)	measurement of clinical parameters clinical attachment loss in millimeters	6 months
Secondary	assessment of inducible nitrous oxide synthase levels	measurement of inducible nitrous oxide synthase levels in different age groups before the procedure and after using Elisa kit.	3 months