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Evaluation of Salivary Galectin-8, Galectin-9 and RANKL Levels of Individuals With Different Periodontal Diseases

Periodontal Diseases Clinical Trial

Official title:
Assessment of Saliva Galectin-8, Galectin-9 and RANKL Levels in Individuals With Different Periodontal Diseases

Clinical Trial Summary

The aim of this study is; detection of Galectin-8, Galectin-9 and RANKL levels in saliva samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between these values and clinical parameters of periodontal diseases. Materials and methods: Samples of saliva were obtained from 60 systemically healthy non-smoker individuals with periodontitis (P, n=20), gingivitis(G, n=20) and healthy periodontium (S, n=20). Full-mouth clinical periodontal measurements including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine Galectin-8, Galectin-9 and RANKL levels in the biological samples.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06404476
Study type Interventional
Source Izmir Katip Celebi University
Contact Kübra Aydin
Phone +905365805175
Email kubra.aydin.er@icloud.com
Status Recruiting
Phase N/A
Start date May 3, 2024
Completion date June 24, 2025
View Details
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