Coconut Oil in Treatment of Periodontitis

Periodontal Diseases Clinical Trial

Official title:

Efficacy of Locally Delivered Coconut Oil in Management of Stage II and III Grade B Periodontitis. A Randomized Controlled Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06384638
• Other study ID #: coconut periodontitis
• Status: Completed
• Phase: Phase 1
• Start date: February 15, 2022
• Est. completion date: February 9, 2024

Study information

• Verified date: April 2024
• Source: Misr University for Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: February 9, 2024
• Est. primary completion date: January 16, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 35 Years to 60 Years

Eligibility

Inclusion Criteria:

• patients age group >35 years without ant systemic disease

• Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss >3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1.

• Patients with no history of allergies to coconut

Exclusion Criteria:

• smokers

• pregnant

• lactating women

• Teeth with both endodontic-periodontal lesion.

Related Conditions & MeSH terms

• Periodontal Diseases
• Periodontitis

Intervention

Biological:
• topical application of coconut oil
topical application of coconut oil

Other:
• scaling and debridement
scaling and debridement

Locations

Country	Name	City	State
Egypt	Faculty of dentistry at MUST	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Misr University for Science and Technology

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical parameters	clinical attachment loss	3 months
Primary	clinical parameters	Probing depth	3 months
Secondary	Biological parameters	Tumor necrosis factor alpha (TNF- a) levels by using ELISA.	3 months