Periodontal Diseases Clinical Trial
Official title:
Efficacy of Locally Delivered Coconut Oil in Management of Stage II and III Grade B Periodontitis. A Randomized Controlled Clinical Trial
Verified date | April 2024 |
Source | Misr University for Science and Technology |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.
Status | Completed |
Enrollment | 34 |
Est. completion date | February 9, 2024 |
Est. primary completion date | January 16, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 35 Years to 60 Years |
Eligibility | Inclusion Criteria: - patients age group >35 years without ant systemic disease - Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss >3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1. - Patients with no history of allergies to coconut Exclusion Criteria: - smokers - pregnant - lactating women - Teeth with both endodontic-periodontal lesion. |
Country | Name | City | State |
---|---|---|---|
Egypt | Faculty of dentistry at MUST | Giza |
Lead Sponsor | Collaborator |
---|---|
Misr University for Science and Technology |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | clinical parameters | clinical attachment loss | 3 months | |
Primary | clinical parameters | Probing depth | 3 months | |
Secondary | Biological parameters | Tumor necrosis factor alpha (TNF- a) levels by using ELISA. | 3 months |
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