Periodontal Diseases Clinical Trial
Official title:
Evaluation Of Biomarkers Associated With Bone Metabolism İn Patients With Different Periodontal Status
Verified date | January 2023 |
Source | Necmettin Erbakan University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study evaluates the levels of biomarkers associated with bone metabolism in patients with different periodontal conditions.
Status | Completed |
Enrollment | 60 |
Est. completion date | November 5, 2021 |
Est. primary completion date | May 5, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility | Inclusion Criteria: - 18-65 years old. - not having any systemic disease that may affect periodontal status - not smoking and alcohol use - volunteer to participate in the study Exclusion Criteria: - periapical pathologies; - resulting from orthodontics and occlusion extreme forces, including mechanical forces; - chronic high-dose steroid therapy; - radiation or immunosuppressive therapy; - pregnancy; - breastfeeding; - allergy or sensitivity to any medication. - Periodontal therapy or drug therapy for at least 6 months of study participants |
Country | Name | City | State |
---|---|---|---|
Turkey | Necmettin Erbakan University | Konya |
Lead Sponsor | Collaborator |
---|---|
Necmettin Erbakan University |
Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Evaluation of bone metabolism biomarkers in different periodontal conditions | The levels of bone metabolism markers in the saliva of individuals with different periodontal status were compared and the relationship of these markers with periodontal status was examined. | baseline | |
Secondary | Probing pocket depth | Probing pocket depth(PPD) was measured for determining the severity of the disease and clinical outcome. High probing depth shows more severe periodontal disease. | baseline | |
Secondary | Gingival index | The differences in gingival index scores between periodontally healthy and periodontitis.The gingival index was recorded for determining and classifying gingival status. The gingival index (GI) scores each site on a 0 being normal and 3 being severe inflammation characterized by edema, redness, swelling and spontaneous bleeding. | baseline | |
Secondary | Plaque index | The differences in plaque index scores between periodontally healthy and periodontitis. Plaque index (PI) was recorded for determining and classifying oral hygiene status. The plaque index (PI) scores each site on a with 0 being no plaque in gingival area and 3 abundance of soft matter within the gingival pocket and/or on the gingival margin and adjacent tooth surface. | baseline |
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