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Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels — hbD2  

Periodontal Diseases Clinical Trial

Official title:
The Effect of Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels

Clinical Trial Summary

Recent studies have shown that while mouthwashes exhibit antimicrobial properties against bacteria and their products, at the same time showing the cytotoxic effect on living cells in the mouth.29 To the best of our knowledge, there is no information about the toxicity effect of these two mouthwashes, which are highly preferred, on antimicrobial peptides secreted from the oral epithelium. Therefore, our aim in this study is to evaluate the effect of chlorhexidine and essential oil mouthwash on hBD2 and LL-37 in saliva.

Clinical Trial Description

Periodontal health continues with a balanced interaction of the oral microflora with the host defense line. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04946617
Study type Observational [Patient Registry]
Source Istanbul Medeniyet University
Contact Mustafa C Yavuz, PhD
Phone +905056429856
Email muscyz111@gmail.com
Status Not yet recruiting
Phase
Start date July 20, 2021
Completion date December 20, 2021
View Details
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