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Thiol/Disulphide Homeostasis and Vascular Endothelial Growth Factor Levels in Diabetic Children

Periodontal Diseases Clinical Trial

Official title:
Thiol/Disulphide Homeostasis and Salivary Vascular Endothelial Growth Factor Levels in Type 1 Diabetic Patients With Gingivitis

Clinical Trial Summary

The aim of this study to evaluate the vascular endothelial growth factor level and thiol/disulphide homeostasis in saliva of diabetic children with gingivitis.

Clinical Trial Description

Eighty children (44 with type 1 diabetes mellitus and 44 systemically healthy) will be recruited for the study. The children will be divided into four subgroups based on their periodontal and systemic condition: 1) systemically and periodontally healthy children, 2) systemically healthy children with gingivitis, 3) periodontally healthy children with T1DM, and 4) children with T1DM and gingivitis. The plaque index, gingival index, probing pocket depth, will recorded. The vascular endothelial growth factor level determined by ELISA. Native thiol, total thiol and disulphide levels will be measured in saliva. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04470635
Study type Observational
Source Aydin Adnan Menderes University
Contact
Status Completed
Phase
Start date July 25, 2020
Completion date October 1, 2020
View Details
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