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Periapical Periodontitis clinical trials

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NCT ID: NCT01904552 Completed - Clinical trials for Apical Periodontitis

Accuracy of ERCLMDs in Teeth With Apical Periodontitis

ERCLMDs
Start date: September 2012
Phase: Phase 1
Study type: Interventional

The aim of this in vivo study is to evaluate the influence of apical periodontitis (AP) on the accuracy of Dentaport ZX, Raypex 5, and i-Root electronic root canal length measurement devices.

NCT ID: NCT01817413 Completed - Clinical trials for Periapical Periodontitis

Comparison of Two Dental Techniques Used to Treat Teeth Which Have Become Infected or Painful Following Trauma

Start date: February 2011
Phase: Phase 4
Study type: Interventional

Children often damage their front teeth. In approximately 6% of cases, the nerve inside the affected tooth dies (becomes 'non-vital') and natural root development stops. In these cases, the tooth requires a root canal treatment in order to prevent problems such as pain and dental abscesses from arising. However, because the roots of these young teeth are not fully formed, they are weaker and prone to fracture. In addition, root canal treatment is difficult because a root canal filling cannot be placed in a tooth which is not yet fully formed, due to the fact that the root has an 'open' end. To enable root canal treatment to be carried out, a 'barrier' must be placed at the end of the 'open' root. This can be done using materials called Calcium Hydroxide or Mineral Trioxide Aggregate (MTA). These materials are placed inside the root and sealed into the tooth. However, although they help to provide a barrier, they do not help to strengthen the walls of the root. Treatment with these materials requires multiple visits to the dentist, over a period of up to 18 months. There is evidence to suggest that an alternative treatment involving 'revascularisation' (recovery of the blood supply to the tooth) and the use of a triple antibiotic paste allows 'natural' root growth to restart, and also strengthens the walls of the root. Treatment can often be carried out in just two visits. The aim of this study is to discover whether there is a difference between one of two methods of treating non-vital teeth with open ends. It is thought that there will be no significant differences seen between the results of the two techniques. Children with teeth that fall into this category and require root canal treatment will be given one of two treatments, both of which aim to treat infection, close the root end and to allow healing to take place. Teeth will receive one of the following methods of root treatment: 1. Revascularisation (recovery of the natural blood supply to the tooth) following placement of an antibiotic paste into the tooth root. The aim of this treatment is to allow 'natural' root growth to restart. Root growth will allow the tooth to form at barrier at the end of the root. No root canal filling will then be necessary. 2. Closure of the open root end by placement of an artificial barrier at the end of the root so that a root canal filling can then be placed. This will be done with a dental material called Mineral Trioxide Aggregate (MTA). Non-vital teeth with an open end are routinely treated in this way at Liverpool Dental Hospital.

NCT ID: NCT01799187 Recruiting - Clinical trials for Periapical Periodontitis

Research of Revascularization in Immature Teeth With Periapical Periodontitis

Start date: July 2012
Phase: N/A
Study type: Interventional

Revascularization is an alternative new treatment of immature permanent teeth with necrotic pulp nowadays while apexification is the traditional therapy. The investigators suppose that revascularization is superior to apexification at developing the root of immature permanent teeth and reducing the risk of root fracture,and the research is designed.

NCT ID: NCT01312194 Completed - Clinical trials for Periapical Periodontitis

Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients

PHAP
Start date: May 2004
Phase: N/A
Study type: Interventional

The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients. Moreover, it is also observed the frequency of postoperative pain in endodontic treatment.

NCT ID: NCT01215201 Completed - Clinical trials for Periodontal Diseases

Diode Laser Study for Periodontal Maintenance Patients

Start date: May 1, 2010
Phase: N/A
Study type: Interventional

This study tries to determine whether the additional use of laser with "cleaning" (known as scaling and root planning) will result in the reduction of inflammation, reduction of bleeding upon examination and reduction of pocket depth in patients who are being maintained on a regular basis but have pocket depths that are ≥5mm with bleeding. When a pocket is bleeding, it is inflamed. It is usually "cleaned" with periodontal instruments (root-planed) to establish health. Some research also advocates using laser therapy to treat a bleeding pocket. Laser therapy is presently being performed in some dental offices and dental colleges. This research is trying to see if the additional laser therapy is beneficial.

NCT ID: NCT00762840 Recruiting - Clinical trials for Periapical Periodontitis

Safety and Efficacy of the Apexum Ablator

Start date: October 2006
Phase: N/A
Study type: Interventional

The study is designed to test the hypothesis that there is a difference in healing kinetics and healing rate between teeth treated by conventional endodontic procedure alone and those in which such procedure was supplemented with the Apexum Ablator protocol

NCT ID: NCT00226148 Completed - Periodontitis Clinical Trials

Immediate Implant Placement in the Molar Regions

Start date: September 2005
Phase: Phase 0
Study type: Interventional

The purpose of this study is to look at the bonehealing when a molar has been extracted and immediately replaced by an implant leaving some defects around the implant. The defects are being treated in three different with the hypothesis that the three ways of treatment result in equal bonehealing.

NCT ID: NCT00223470 Completed - Clinical trials for Chronic Apical Periodontitis of Pulpal Origin

Cytokine Regulation of Periradicular Pain in Humans

Start date: October 2002
Phase: N/A
Study type: Observational

This clinical trial evaluates the role of cytokines in patients needing root canal treatment with diagnosis of necrotic pulp and chronic apical periodontitis

NCT ID: NCT00223379 Completed - Clinical trials for Chronic Apical Periodontitis of Pulpal Origin

Longitudinal Endodontic Study of Apical Preparation Size

Start date: December 2002
Phase: N/A
Study type: Interventional

This protocol is for a clinical trial evaluating the clinical success of root canal therapy performed on teeth with chronic apical periodontitis of pulpal origin with either large or small apical root canal preparation techniques.

NCT ID: NCT00223327 Completed - Clinical trials for Periapical Periodontitis

Measurement of Bite Force in Humans

Start date: March 2005
Phase: Phase 0
Study type: Observational

This protocol is for a clinical trial to evaluate the reliability of the bite fork as a diagnostic instrument in subjects with pulpal necrosis and apical periodontitis.