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Periapical Disease clinical trials

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NCT ID: NCT06342830 Not yet recruiting - Periapical Disease Clinical Trials

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Start date: June 20, 2024
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to compare the effects of different intracanal medication between endodontic retreatment visits in previously failed root canal treatment patients (single root canal anteriors or premolars teeth). The main question it aims to answer are: - Is natural and synthetic intracanal Medicament effective in reducing or complete healing of Periapical lesions or not? the researchers will compare the effect of different intracanal dressing including: - nanocurcumin gel - curcumin gel - ciprofloxacin +ibuprofen gel - calcium hydroxide Paste as control group in between the endodontic retreatment visits to see if these medicaments work well on periapical lesion healing this outcome measured by Cone beam CT at base and after 1 year follow up period

NCT ID: NCT04358887 Active, not recruiting - Periapical Disease Clinical Trials

Effect of Piezoelectric Surgery on Quality of Life and Periradicular Healing After Endodontic Surgery

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This study will compare the effect of piezo Vs bur on quality of life and healing after endodontic surgery.

NCT ID: NCT00490165 Completed - Diabetes Clinical Trials

Periodontal and Periapical Inflammation and Pregnancy

Start date: March 2007
Phase: N/A
Study type: Observational

This is a retrospective chart review of patient records at the University of Mississippi Medical Center. We are not actively recruiting patients for this study. Recent animal studies we conducted showed that periapical abscesses during pregnancy cause a systemic inflammatory response in the mother. Also due to the increase in TNF-alpha (an inflammatory cytokine) the mother also become insulin resistant and thus developed gestational diabetes. Periodontal inflammation has been shown in the research to lead to low-birth weight and pre-term birth. We are looking retrospectively to see if an association exists in charted data between periapical and periodontal inflammation and adverse pregnancy outcomes.

NCT ID: NCT00228280 Active, not recruiting - Alveolar Bone Loss Clinical Trials

Periapical Bone Healing After Apicectomy With and Without Retrograde Root Filling

Start date: January 2005
Phase: Phase 1/Phase 2
Study type: Interventional

Ph.D project: Periapical bone healing after apicectomy with and without retrograde root filling. The aim of this study is to assess periapical bone healing after apicectomy without a filling and apicectomy combined with a retrograde filling material, MTA. Further, we will estimate risk factors in non-healing cases. Study hypothesis: There is no difference in treatment outcome between: Periapical bone healing after apicectomy with retrograde root filling and Periapical bone healing after apicectomy without retrograde root filling