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Perfusion clinical trials

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NCT ID: NCT06220357 Completed - Perfusion Clinical Trials

Diluted Indocyanine Green Angiography: a Novel Approach to Free Flap Perfusion Evaluation in Reconstructive Microsurgery

Start date: October 10, 2022
Phase: N/A
Study type: Interventional

The evaluation of perfusion in free flaps is crucial in clinical practice. Currently, the gold standard for evaluation is subjective through clinical assessment. However, indocyanine green angiography (ICGA), a tool that uses a near-infrared (NIR) camera to depict and monitor flap vascularization, offers an objective and reproducible alternative. The population in this study were divided into three equal groups, where each groups were assessed with Indocyanine Green (Aurogreen®, Aurolab, Tamil Nadu, India). The study was conducted with three distinct concentrations of ICGA: 5 mg/mL (100% standard concentration), 2.5 mg/mL (50%), and 0.5 mg/mL (10%). Indocyanine green was given in immediate postoperative manner, after the patient defect has been reconstructed with free flap.

NCT ID: NCT04233177 Completed - Clinical trials for Perioperative/Postoperative Complications

The Effect of Trendelenburg Position on CCA Blood Flow

Start date: January 13, 2020
Phase:
Study type: Observational

The investigators will evaluate the change of the common carotid artery blood flow according to patient's position and penumoperitoneum.

NCT ID: NCT03644420 Completed - Clinical trials for Osteoarthritis, Knee

Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis

Chondrolike
Start date: May 2013
Phase:
Study type: Observational

Patients with osteoarthritis of the knee undergo visible joint changes in radiology and Magnetic resonance imaging (MRI) tests, but also clinically and histologically. The area of greatest change is at the subchondral/cartilage bone junction. Investigators will determine the association between preoperative clinical evaluation (IKDC and Womac scores), radiological classifications and histopathology. In addition, the role of inflammation in the pathogenesis of osteoarthritis is being given major interest, and inflammation is closely linked with vascularization. It was recently demonstrated that dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) could identify the subchondral bone marrow vascularization changes occurring in osteoarthritis in animals. These changes appeared before cartilage lesions were visible and were correlated with osteoarthritis severity. Thus the opportunity to obtain an objective assessment of bone vascularization in non-invasive conditions in humans might help better understanding osteoarthritis pathophysiology and finding new biomarkers. Investigators hypothesized that, as in animals, DCE-MRI has the ability to identify subchondral bone marrow vascularization changes in human osteoarthritis.

NCT ID: NCT03180060 Completed - Coronary Disease Clinical Trials

Meta-Analysis of Stress Myocardial Perfusion Imaging

Start date: August 3, 2015
Phase: N/A
Study type: Observational

Background: Detection of coronary artery disease (CAD) is important due to its high prevalence and its medical and economic implications. Purpose: A systematic review of the diagnostic performance of stress echocardiography (Echo), SPECT, cardiac magnetic resonance (CMR), CT Perfusion (CTP) and PET versus invasive coronary angiography (ICA) or fractional flow reserve (FFR) using hierarchical summary ROC (HSROC) methods. Data Sources: MEDLINE, EMBASE and SCOPUS for literature published in English or Spanish from January 1970 to December 2015. Study Selection: For inclusion, studies had to meet the Cochrane guidelines, had to evaluate the sensitivity and specificity methods, and use ICA and/or FFR. Only those studies with STARD methodology ≥60% were included. Data Extraction: Ten investigators extracted patient and study characteristics and 4 resolved any disagreements.

NCT ID: NCT03151369 Completed - Perfusion Clinical Trials

Visual Pain Score and Perfusion Index in Postoperative Patients

Start date: April 18, 2017
Phase: N/A
Study type: Interventional

The relationship between visual pain score and perfusion index in postoperative patients.

NCT ID: NCT03121443 Completed - Perfusion Clinical Trials

Patient Positions and Perfusion Index

Start date: May 10, 2017
Phase: N/A
Study type: Observational

The association between patient positions including supine,prone, trendelenburg,reverse trendelenburg,45 degrees back up sitting position, 45 degrees legs lifted supine position and perfusion index.

NCT ID: NCT03048162 Completed - Perfusion Clinical Trials

The Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index

Start date: February 13, 2017
Phase: N/A
Study type: Interventional

This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be randomly divided into three groups. Baseline, 5th, 10th, 15th, 20th, 25th and 30th min non-invasive blood pressure, oxygen saturation, heart rate, room temperature, perfusion index and pulse variability index will be measured and recorded.

NCT ID: NCT02646150 Completed - Ischemia Clinical Trials

Clinical Use of Magnetic Resonance Perfusion Imaging to Qualitatively Assess Adequate Distal Perfusion After Endovascular Revascularization in Critical Limb Ischemia

MR CLI
Start date: December 12, 2015
Phase:
Study type: Observational

This study evaluates the clinical effectiveness of Magnetic Resonance(MR) perfusion imaging to qualitatively assess adequate distal perfusion after endovascular revascularization in Critical Limb Ischemia

NCT ID: NCT02612883 Completed - Perfusion Clinical Trials

Flux Measurement and Outcome in Major Abdominal Surgery

FLUX
Start date: November 18, 2015
Phase:
Study type: Observational

Tissue perfusion is a critical factor for tissue regeneration and healing of anastomoses. Compromised microperfusion in the area where the anastomosis is sited likely contributes to leaks, but until now there has not been an easy and reliable technique to intraoperatively evaluate microperfusion. Objectives: To assess the association of intraoperative flux measurement with postoperative outcome of patients undergoing major abdominal surgery. Trial design: Prospective observational study. Flux measurement will be carried out using the moorVMS-LDF DUAL CHANNEL Laser Doppler Blood Flow system. The flux probe will be applied on the respective organs (i.e. esophagus, stomach, liver, pancreas, colon, rectum) and measurements will be documented after a stable signal has been obtained.

NCT ID: NCT01168557 Completed - Cardiac Output Clinical Trials

Stress Echo and Electric Impedance Tomography (EIT) Pilot Study

Start date: July 2010
Phase: N/A
Study type: Interventional

Electric Impedance Tomography (EIT) is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice of the thorax.It is a radiation free, non- invasive and portable lung imaging technique. Impedance changes in lung ventilation as well as in lung perfusion can be shown. To investigate lung perfusion by EIT measurements, cardiac output measured by routinely undergone stress echocardiography at rest and stress are compared to parameters measured by EIT.