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Peptic Ulcer clinical trials

View clinical trials related to Peptic Ulcer.

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NCT ID: NCT04636866 Completed - Clinical trials for Helicobacter Pylori Infection

The Prevalence of Helicobacter Pylori in Shanghai, 2013 to 2019

Start date: February 10, 2020
Phase:
Study type: Observational

The study was a cross-sectional single-center study, conducted at Renji Hospital, Shanghai Jiaotong university school of medicine. We retrieved the medical records of all patients who had undergone upper gastrointestinal endoscopy from January 1, 2013 through December 31, 2019. The medical records were analyzed for the prevalence of H. pylori infection in patients with peptic ulcers.

NCT ID: NCT04536428 Active, not recruiting - Clinical trials for Peptic Ulcer Hemorrhage

ClearEndoclip Versus EZ Clip for Upper Gastrointestinal Ulcer Bleeding

Start date: August 24, 2020
Phase: N/A
Study type: Interventional

We are going to conduct a comparative study to analyze the clinical effectiveness and user convenience of EZ clips that have been used in upper gastrointestinal ulcer bleeding and newly developed clip (ClearEndoclip, FineMedix, Taegu) in Korea. 1) Research hypothesis and purpose - This study was designed to prove the hypothesis that the hemostatic effect of newly developed endoscopic clip (ClearEndoclip, FineMedix, Taegu, Korea) is not inferior to that of EZ clip (Olympus, Tokyo, Japan) in the treatment of hemostasis for patients who visited the upper gastrointestinal ulcer bleeding. - This study was designed as a multi-center (9 institutions), open-labelled, randomized comparative clinical trial (1:1 ratio).

NCT ID: NCT04447170 Recruiting - Surgery Clinical Trials

Laparoscopic Versus Open Repair of Peptic Ulcer Perforation

LOREPUP
Start date: January 1, 2017
Phase:
Study type: Observational

Although laparoscopic repair (LR) of perforated peptic ulcers (PPUs) has long been accepted, clinical evidence comparing LR versus open repair (OR) remains lacking. The aim of this study is to evaluate the feasibility, safety and outcome of laparoscopic gastric repair and compare it with the outcome open repair by relying on a propensity score matching statistical technique

NCT ID: NCT04432233 Recruiting - Clinical trials for Helicobacter Pylori Infection

Intravenous Triple Therapy in the Treatment of Helicobacter Pylori Infection and Related Complications Caused by Active Peptic Ulcer Disease

Start date: June 15, 2020
Phase: Phase 4
Study type: Interventional

Helicobacter pylori infection causes active peptic ulcer disease and related complications like bleeding and pyloric obstruction. Usually, clinicians tended to treat Helicobacter pylori infection after active peptic ulcer disease and related complicaitons getting healed, which spent time and money. This study is designed to evaluate the efficacy and safety of intravenous administration of metronidazole, levofloxacin and esomeprazole triple therapy in the treatment of Helicobacter pylori infection combined with peptic ulcer disease related complications.

NCT ID: NCT04407832 Withdrawn - Clinical trials for Peptic Ulcer Bleeding

Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy

lowdosePPI
Start date: August 2011
Phase: N/A
Study type: Interventional

The investigators used two different doses of esomeprazole (40 mg IV q.d. and 40 mg IV q6h for three days followed by esomeprazole 40 mg q.d. orally in two groups) after successful endoscopic therapy with heat probe therapy or hemoclip placement. The goal of this study is to assess the outcomes of two different regimens of low vs. high dose of intravenous esomeprazole after endoscopic therapy in patients with peptic ulcer bleeding.

NCT ID: NCT04366583 Completed - Clinical trials for Bleeding Peptic Ulcer

Argon Plasma Coagulation vs Hemoclipping for Bleeding Peptic Ulcers

Start date: February 9, 2012
Phase: Phase 4
Study type: Interventional

Endoscopic treatment is recommended for initial hemostasis in nonvariceal upper gastrointestinal bleeding. However, the additional hemostatic efficacy of argon plasma coagulation (APC) has not been widely investigated. We designed a randomized trial comparing APC plus injection therapy vs hemoclipping plus injection therapy for peptic ulcer bleeding.

NCT ID: NCT04239118 Completed - Ulcer Hemorrhage Clinical Trials

New Technologies for Endoscopic Treatment of Bleeding Gastroduodenal Ulcers

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

The purpose of the study was to improve treatment results of patients with bleeding gastroduodenal ulcers by endoscopic applications of autoplasma, enriched with platelets and granular sorbent aseptisorb-A.

NCT ID: NCT04211194 Completed - Clinical trials for Peptic Ulcer Hemorrhage

Registry for Upper Gastrointestinal Bleeding

Start date: October 1, 2019
Phase:
Study type: Observational

This project aims to evaluate the data on all patients undergoing endoscopic therapy for upper gastrointestinal bleeding.

NCT ID: NCT04194060 Completed - Emergencies Clinical Trials

ERAS vs Conventional Approach in Peptic Perforation-RCT

ERASE
Start date: January 20, 2020
Phase: N/A
Study type: Interventional

This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.

NCT ID: NCT04170270 Not yet recruiting - Clinical trials for Bleeding Peptic Ulcer

Oral Omeprazole in Bleeding Peptic Ulcer

Start date: November 2019
Phase: Early Phase 1
Study type: Interventional

Find out if there is a significant difference between clinical outcome among the patients with bleeding peptic ulcer treated with oral omeprazole compared to those treated with intravenous omeprazole.