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Clinical Trial Summary

Interventional study evaluating the efficacy of an immunotherapy (pembrolizumab) in combination with a targeted therapy (vorinostat) in patient with recurrent and/or metastatic squamous cell carcinoma (localisations : head and neck, lung, cervix, anus, vulva, and penis)


Clinical Trial Description

Open-label, non-randomized, multi-center, basket phase II trial, evaluating the efficacy of pembrolizumab in combination with vorinostat in adult patients with recurrent and/or metastatic squamous cell carcinoma of different locations. Antitumor activity of the combination will be evaluated using the objective response rate (ORR) during treatment (investigator assessment). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04357873
Study type Interventional
Source UNICANCER
Contact
Status Active, not recruiting
Phase Phase 2
Start date October 28, 2020
Completion date January 2025

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