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Pelvic Pain clinical trials

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NCT ID: NCT05698355 Recruiting - Pelvic Pain Clinical Trials

Telerehabilitation in Chronic Pelvic Pain

CPP
Start date: January 16, 2023
Phase: N/A
Study type: Interventional

Objective: Physical therapists utilize telerehabilitation as the common term for telehealth applications. Many physiotherapists worked as telehealth providers during the coronavirus pandemic. The objective of the study will show the efficacy of Telerehabilitation-Based Physical Therapy (TBPT) on pain intensity and treatment satisfaction in patients with chronic pelvic pain. Method: This study is a prospective study of patients with chronic pelvic pain.42 participants will include the study. Patients who have any other distribution pattern of pelvic pain were equally considered for therapy. Women age between 18-50 years will be include. Their symptoms should be one of these follows such as chronic pain in pelvic region, hyperalgesia in vulva, and pain during sitting or intercourse. They will get diagnosed by a gynecologist who is a multidisciplinary team comprising and referred to a pelvic health physiotherapist. Prior to treatment patients will complete questionnaires and interview a pelvic health physiotherapist. Pain symptoms will be assessed with the Visual Analog Scale (VAS) and The Pelvic Pain Impact Questionnaire (PPIQ) before and after treatment. Patient Global Impression of Improvement (PGI-I) for evaluating patient satisfaction after treatment. Women with chronic pelvic pain will be treated for 16 sessions (an hour for each session) in 8 weeks with the TBPT technique by the same pelvic health physiotherapist (AB). Patients will apply internal and external trigger point release therapy and self-massage techniques by themselves with Telerehabilitation-Based Physical Therapy.

NCT ID: NCT05670353 Recruiting - Endometriosis Clinical Trials

Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)

DREAMLAND
Start date: January 3, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabis extract in women with endometriosis who have already undergone hormonal contraceptive treatment and surgery without satisfactory response.

NCT ID: NCT05658874 Recruiting - Clinical trials for Interstitial Cystitis

A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain

Start date: December 1, 2022
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after treatment using a painful bladder scale. The participant will have 5 visits to evaluate your symptoms with questionnaires, at least one procedural visit, and must participate in physical therapy and some kind of behavioral health therapy. This study will assess participant response to a bundled-care approach to chronic bladder pain both pre-and post intervention as well as compared to a group of participants receiving typical care.

NCT ID: NCT05622955 Recruiting - Endometriosis Clinical Trials

Endometriosis Group Care

PEEPS
Start date: February 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the effectiveness of the Peer Empowered Endometriosis Pain Support (PEEPS) program in people living with endometriosis-related pelvic pain. The main question[s] it aims to answer are: - Is PEEPS effective at decreasing pain interference and improving patient-reported quality of life outcomes? - What are the barriers and facilitators to PEEPS implementation? Participants will engage in eight weekly 2-hour sessions led by an endometriosis specialist, pain psychologist, pelvic floor physical therapist, and yoga instructor. At these sessions they will participate in peer support, education, mindfulness, and yoga.

NCT ID: NCT05617118 Recruiting - Chronic Pain Clinical Trials

BTA vs Baclofen for Pelvic Myofascial Pain Syndrome

BvsB
Start date: December 1, 2022
Phase:
Study type: Observational

The aim of the study is to test the hypothesis that oral taking of baclofen in therapeutic dosage for 60 days is equally effective as injection of botulinum toxin type "A" in the area of trigger points of the pelvic muscles.

NCT ID: NCT05570786 Recruiting - Pelvic Pain Clinical Trials

Subdermal Implant-bioabsorbable Gestrinone Pellet for Endometriosis Pelvic Pain Treatment

GLADE
Start date: February 13, 2023
Phase: Phase 2
Study type: Interventional

Pelvic pain is considered a symptom of multifactorial origin among which Endometriosis is the main gynecological cause affecting 5-10% of worldwide women in their reproductive years, negatively impacting their quality of life and work efficiency. Treatment of endometriosis-associated pelvic pain is challenging and there are surgical and/or hormonal treatments available with variable endpoints. Gestrinone is a synthetic derivative of 19-nortestosterone with anti-estrogen, anti-progestin, androgenic, and weak estrogen-like action. Previous studies show that the oral treatment with Gestrinone induced an improvement in symptoms associated with endometriosis but with adverse events such as androgenization and uterine bleeding. Parenteral administration of Gestrinone could be effective to treat pain symptoms secondary to endometriosis and minimize these adverse events. This study evaluates the safety and tolerability of subdermal implant-bioabsorbable gestrinone pellet use in women with pelvic pain secondary to endometriosis after 6 months of Gestrinone pellet insertion versus placebo pellet. PK profile of the gestrinone pellet will be monitored.

NCT ID: NCT05540353 Recruiting - Endometriosis Clinical Trials

Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients With Endometriosis.

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population. A prospective single-blinded randomized controlled trial will be performed evaluating the change in pelvic pain and sexual satisfaction scores from baseline to 6 weeks after treatment with transvaginal photobiomodulation therapy or sham therapy. Treatment will involve 9 planned treatment sessions over 3-4 weeks. 40 women will be included in the study.

NCT ID: NCT05538689 Recruiting - Pelvic Pain Clinical Trials

Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)

SOUL
Start date: November 20, 2022
Phase: Phase 4
Study type: Interventional

In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the potential to delay the recurrence of fibroid symptoms, prolong the improved quality of life and delay the need for re-intervention after uterine sparing surgery versus the routine standard of care.

NCT ID: NCT05537207 Recruiting - Pelvic Pain Clinical Trials

Laser at Lumbar Acupoint on Pain and Quality of Life in Chronic Pelvic Pain

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

To investigate the effect of low-level laser at lumbar sensitized acupoint on pain perception in chronic pelvic pain. BACKGROUND: chronic pelvic pain is one of the serious problems in the female, resulting in pain and less physical activity.

NCT ID: NCT05489133 Recruiting - Clinical trials for Post Traumatic Stress Disorder

Early Psychological Intervention After Rape

EIR
Start date: June 14, 2022
Phase: N/A
Study type: Interventional

Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape. A modified protocol based on Prolonged Exposure Therapy (mPE), has been developed, consisting of three to five once or twice weekly 60 minutes sessions, and studies indicate that if implemented early after rape, mPE may prevent the development of PTSD. The aim of the study is to conduct a multi-site (4 Sexual assault care centers in Norway) randomized control trial (RCT) in which patients are recruited early after rape, and randomized to intervention (mPE) or treatment as usual (TAU).