Clinical Trials Logo
  1. Home
  2. Pediatrics
  3. NCT04491032

Pediatric Caudal Injection Volume on Optic Nerve Sheath Diameter and Cerebral Oxygenation

Pediatrics Clinical Trial

Official title:
The Effect of Caudal Epidural Injection Volume on Optic Nerve Sheath Diameter and Cerebral Oxygenation in Pediatric Cases

Clinical Trial Summary

Caudal anesthesia is a commonly used neuraxial anesthesia method for children. Injection of a certain volume of fluid into the epidural space for cauda anesthesia may push some cerebrospinal fluid towards the head, which may lead to mild increase of pressures inside the head. Such mild changes are compensated well by healthy individuals and no clinical sequel is seen, however at-risk populations may be affected. We aim to see how different amounts of fluid injected into the epidural space may change two clinical parameters affected by intracranial pressure to determine if a lower volume is safer than a higher one.

Clinical Trial Description

Caudal epidural injection of local anesthetic solution is a common neuraxial anesthesia technique that provides excellent peri-operative analgesia in children. Unfused sacral hiatus allows for easy and safe access into the epidural space. Anatomically, injection of a certain volume of fluid over the dural sac inside the closed spinal canal can push the cerebrospinal fluid cranially. This push may lead to increased intracranial pressure. We will measure two findings affected by intracranial pressure (optic nerve sheath diameter and cerebral oxygenation) and compare the effects of two different volumes of caudal injections on these measures. Children with closed fontanelles and scheduled to undergo elective surgery, for which caudal anesthesia is an effective method for peri-operative analgesia, will be recruited for this study. Injection volume will be determined depending on the level of analgesia required for the surgical procedure. Ultrasonographic measurements of optic nerve sheath diameter and near-infrared spectrometry measurement of cerebral oxygenation will be taken before and after caudal anesthesia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04491032
Study type Interventional
Source Istanbul University
Contact
Status Completed
Phase N/A
Start date February 15, 2019
Completion date March 15, 2022
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT05975658 - WIReD: Wireless Interstage Remote Device Study
Completed NCT03921346 - Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR N/A
Not yet recruiting NCT04087070 - Blood Pressure Estimation Using Noninvasive Biosignals During Pediatric Anesthesia
Completed NCT04301206 - Videos and Simple Text to Empower Parents to Handle Their Sick Children N/A
Recruiting NCT06273228 - Parenting Young Children in Pediatrics N/A
Recruiting NCT05480930 - Improving Nighttime Access to Care and Treatment; Part 4-Haiti N/A
Not yet recruiting NCT05815563 - Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Recruiting NCT02908113 - Visual Perception in Preterm Infants N/A
Recruiting NCT02556541 - Ultrasound-guided Peripheral Vascular Access in Children N/A
Not yet recruiting NCT01678066 - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor N/A
Completed NCT04993599 - Evaluation of Social Robot Usability for Pediatric Patients and Carers N/A
Completed NCT05537168 - Bayesian Networks in Pediatric Cardiac Surgery
Completed NCT01603628 - BOTOX® Treatment in Pediatric Lower Limb Spasticity Phase 3
Completed NCT01603615 - BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity Phase 3
Completed NCT06098105 - Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics N/A
Completed NCT01418846 - Determination of Voriconazole Levels in Saliva - Validation in Specific Subsets of Patients N/A
Completed NCT01460329 - Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO N/A
Withdrawn NCT00666393 - An Evaluation of Safety of the Fentanyl Transdermal System for Management of Acute Post-Operative Pain in Pediatric Patients Phase 3
Recruiting NCT03337581 - Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric Phase 4
Recruiting NCT05275881 - Impact of Virtual Reality in Pediatric Hematology and Oncology N/A