Pediatric Obesity Clinical Trial
Official title:
Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status
Acute exercise has been shown to affect subsequent energy intake in obese adolescents.
Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the
individual maximal capacities) can reduce energy intake at the following meal in obese
adolescents, with no modification of his appetite feelings.
Although this results has been replicated several times, it remains unknown if those
nutritional adaptations are due to post-exercise modifications of some gastro-peptides
implicated in appetite control, as detailed in adults.
The aim of this work is to question whether or not post-exercise energy intake is explained
by appetite-regulating hormones that are affected by the exercise bout in both lean and
obese youth.
After an first medical visit to ensure that the adolescents have the ability to complete the
whole study, the participants will have to complete several clinical examinations:
- anthropometric measurements
- Body composition assessed by dual energy x-ray absorptiometry
- Maximal aerobic test
They will then randomly complete the following conditions:
- CON: a control day without exercise;
- HIE: an exercise day with an exercise set at 75% of the capacities
- LIE: an exercise day with an exercise set at 40% of the capacities
The exercises or the rest condition will be done by the end of the morning and a buffet meal
will be proposed during which the participants will be asked to eat as much as wanted.
Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to
assess the main appetite regulating hormones involved in appetite regulation (PYY,
Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular
interval using visual analogue scales.
;
Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Basic Science
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