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Pediatric Cancer clinical trials

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NCT ID: NCT05305950 Active, not recruiting - Pediatric Cancer Clinical Trials

Barriers and Facilitators in Access to OT/PT in Pediatric Cancer Survivors

Start date: December 17, 2021
Phase:
Study type: Observational

This study aims to identify the modifiable facilitators and barriers to occupational and physical therapy care for children during and after cancer treatment that may be contributing to disparities in health outcomes. The investigators will identify these facilitators and barriers by surveying and interviewing healthcare administrators at MD Anderson Cancer center. The investigators will also survey and interview physicians, advanced practice providers, and occupational and physical therapists to obtain their feedback on these issues.

NCT ID: NCT05041075 Active, not recruiting - Pediatric Cancer Clinical Trials

Effect of Weighted Blankets on Anxiety for Pediatric Oncology Patients

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

The use of weighted blankets has been studied in the adult population but there is a lack of evidence to determine their benefit among a pediatric population, specifically oncology pediatric patients. Pediatric oncology patients routinely experience anxiety during therapy and as cure rates increase, attention has progressively turned to treating psychosocial aspects of care.

NCT ID: NCT04674150 Active, not recruiting - Surgery Clinical Trials

A Pilot Randomized Controlled Trial for Feasibility of Administering an AR Game to Postoperative Pediatric Cancer Patients

GAMING
Start date: January 13, 2021
Phase: Phase 1
Study type: Interventional

This is a pilot study to evaluate the feasibility of SpellBound's AR (augmented reality)-enabled scavenger hunt use among 20 pediatric cancer patients undergoing surgery.

NCT ID: NCT04610736 Active, not recruiting - Pediatric Cancer Clinical Trials

TEMOkids Study : A Phase I Pediatric Study for KIMOZO, Oral Suspension of Temozolomide

Start date: March 16, 2021
Phase: Phase 1
Study type: Interventional

Non-randomized, international, multi-centre, open-label, single arm study to determine the pharmacokinetic (PK) parameters of a single dose of an oral suspension of temozolomide (KIMOZO) in the pediatric population aged 1 year and over.

NCT ID: NCT04479514 Active, not recruiting - Pediatric Cancer Clinical Trials

Preventative Skin Care for Children Undergoing Targeted CNS Tumor Therapy

Start date: October 1, 2020
Phase: Phase 2
Study type: Interventional

This research study is examining a preventive skin care regimen for children diagnosed with a brain tumor and receiving anti-cancer therapy with a MEK, Pan-RAF, or BRAF inhibitor.

NCT ID: NCT04446728 Active, not recruiting - Pediatric Cancer Clinical Trials

Implementation of Family Psychosocial Risk Assessment in Pediatric Cancer

PAT
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The diagnosis and treatment of pediatric cancer adversely affects multiple levels of the social ecology, including patient and caregiver physical and psychosocial health. It is the strong recommendation from the first Standard of the Psychosocial Standards of Care in Pediatric Cancer that cancer centers engage in universal, systematic, psychosocial risk screening for newly diagnosed patients and their families. Universal screening at diagnosis fosters early identification of psychosocial risks and provides the opportunity to match psychosocial care to the level of family need for more equitable, effective and integrated services. However, few programs offer such care in an efficient, comprehensive, and consistent manner, potentially resulting in insufficient care that magnifies inequities in outcomes. To support pediatric cancer centers in their goal of meeting the first Standard of Psychosocial Care, this study will compare two implementation strategies for the Psychosocial Assessment Tool (PAT), a validated parent report screener of family psychosocial risk in English and Spanish, in a cluster randomized trial across 18 pediatric cancer programs in the United States.

NCT ID: NCT04118062 Active, not recruiting - Clinical trials for Triple Negative Breast Cancer

Communicating With Patients on Cancer Resistance to Treatment: the Development of a Communication Tool. (HECTOR)

Start date: February 2, 2021
Phase: N/A
Study type: Interventional

Resistance to treatment is one of the major themes in cancer research. Despite this, the definition and clinical implications of resistance to treatment remain under-explored, and patient-physician communication in this context still constitutes a challenge. When resistance to cancer treatments occurs, physicians not only have to explain to the patient the phenomenon of resistance, often based on complex results (biological results, genomic tests, imaging, etc.), but also need to offer alternative therapies, whilst fostering shared medical decision-making. These different tasks are particularly challenging for clinicians, especially since there are large individual differences at patient level. Indeed, each patient has his or her own unique information needs, capacity for understanding, and level of desire to participate in treatment decisions.

NCT ID: NCT03925831 Active, not recruiting - Oncology Clinical Trials

Trend Analysis of the Service of Pediatric Palliative Care

Start date: April 2, 2019
Phase:
Study type: Observational

Palliative care has received considerable attention in Taiwan in recent years. The relevant research has been widely conducted for palliative care in adult population. However, the research in children population is relatively insufficient. In the limited studies, most of them are the experiences generated from individual institutions. This study is going to retrieve the data from 2008-2017 National Health Insurance Research Database, Cancer Registry Database, Death Registry Database and other relevant materials in order to analyze the trends of using pediatric palliative care service, the types of services, the timing of initiating palliative care, and the preference of using palliative care service among different life span in the past decade. In addition, the study will examine the differences of the timing of initiating of pediatric palliative care service and the types of diseases among different characteristics of children and healthcare providers. And the study will discuss how pediatric palliative care services affect medical costs.

NCT ID: NCT03837899 Active, not recruiting - Pediatric Cancer Clinical Trials

Durvalumab and Tremelimumab for Pediatric Malignancies

Start date: March 7, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to determine the recommended dose of durvalumab and tremelimumab (immunotherapy drugs) in pediatric patients with advanced solid and hematological cancers and expand in a second phase to test the efficacy of these drugs once this dose is determined.

NCT ID: NCT03739372 Active, not recruiting - Cancer Clinical Trials

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

PNOC008
Start date: November 28, 2018
Phase: N/A
Study type: Interventional

This is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC). The study will use a new treatment approach based on each patient's tumor gene expression, whole-exome sequencing (WES), targeted panel profile (UCSF 500 gene panel), and RNA-Seq. The current study will test the efficacy of such an approach in children with High-grade gliomas HGG.