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Pectus Excavatum clinical trials

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NCT ID: NCT04046835 Not yet recruiting - Pectus Excavatum Clinical Trials

The Effect of Patient Position on the External Haller Index Value Among Patients With Pectus Excavatum

POSITION
Start date: January 2021
Phase:
Study type: Observational

Pectus excavatum is the most common anterior chest wall deformity, affecting up to 1:400 of newborns. The current gold standard to quantify the extent of deformity is by calculating the Haller Index based on a Computed Tomography (CT)-scan. However, as such scans inescapably imply exposure to ionizing radiation, novel imaging techniques have been investigated. Three-dimensional optical surface scanning is a promising new technique to acquire the trunks' three-dimensional (3D) surface topography. Based on this 3D scan, one is able to calculate the external Haller Index that is known to highly correlate with the conventional gold standard Haller Index that is based on internal measures. Both the conventional and external Haller Index are known to be affected by the respiratory phase in which the scan is acquired, however, what is the effect of patient position on the external Haller Index, and if affected, how should one correct for this phenomenon? To investigate this, a retrospective single-centre pilot study will be conducted.

NCT ID: NCT03926078 Recruiting - Pectus Excavatum Clinical Trials

Three-dimensional Optical Surface Imaging as a Diagnostic Tool in Pectus Excavatum

3D PECTUS
Start date: August 21, 2019
Phase: N/A
Study type: Interventional

Pectus excavatum (PE) is the most common anterior chest wall deformity. Currently, a chest radiography (CR) or Computed Tomography (CT) scan is acquired to determine and objectify pectus severity using the Haller Index. Alongside other determinants, the Haller Index value is used in the proces of clinical decision making and determine surgical candidacy. However, cross-sectional imaging based calculation of the Haller Index implies exposure to ionizing radiation that should be limited at all times to diminish the cumulative long-term risks of malignancy. Especially in pectus patients that often concerns children. Three-dimensional (3D) optical surface imaging offers a non-invasive, radiation-free alternative that may be used to obtain thoracic measures and determine pectus severity. However, for 3D images/scans to be used as a diagnostic tool in the proces of clinical decision making and determine surgical candidacy, its diagnostic accuracy should be evaluated. This will be investigated utilizing a pilot study design as no prior accuracy studies are available.

NCT ID: NCT03346876 Recruiting - Surgery Clinical Trials

Autonomic Dysfunction in Patients With Pectus Excavatum.

ADPE
Start date: August 1, 2017
Phase: N/A
Study type: Observational [Patient Registry]

Investigators conducted a pilot study to to evaluate the autonomic function in participants with pectus excavatum before and after Nuss surgery.

NCT ID: NCT03073616 Completed - Pectus Excavatum Clinical Trials

Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children

ECO_NUSS
Start date: April 1, 2017
Phase:
Study type: Observational

This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE) with Nuss repair.

NCT ID: NCT02958683 Completed - Surgery Clinical Trials

Chest Wall Motion Analysis in Disease

CWM
Start date: July 2011
Phase:
Study type: Observational

Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest. Breathing movements may help with diagnosis, assessment of severity or assessing the impact of treatments for chest conditions. The investigators are following people who have a chest disease, measuring their chest wall motion and comparing it to their diagnosis and and how their treatment works. Chest wall motion can be measured in different ways at rest and whilst exercising. Small stickers on the chest can be used to reflect infra red light or visible squares of light can be shone onto the chest without using stickers.

NCT ID: NCT02721017 Completed - Pectus Excavatum Clinical Trials

Cryoanalgesia vs. Epidural in the Nuss Procedure

Start date: May 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether cryoanalgesia provides better pain control for minimally invasive pectus excavatum repair (the Nuss procedure) than thoracic epidural.

NCT ID: NCT02552186 Completed - Pectus Excavatum Clinical Trials

Non-invasive Clinical Pectus Index as a Measurement of Severity in Pectus

Start date: September 2015
Phase: N/A
Study type: Interventional

Pectus excavatum (PE), the most common congenital chest wall deformity, requires surgical repair when the degree of deformity is severe. Currently, the Pectus Index (PI) is used to classify PE severity. Calculation of the PI requires cross-sectional imaging of the chest, usually with computed tomography (CT) or Magnetic Resonance Imaging (MRI), to obtain the necessary measurements. However, CT delivers a high dose of ionizing radiation, which carries cumulative long-term risks of malignancy and MRI can be costly. The purpose of this study is to develop a method whereby accurate chest wall measurements can be obtained to quantify PE severity without the need for cross-sectional imaging.

NCT ID: NCT02528656 Recruiting - Pectus Excavatum Clinical Trials

Physiological Assessments During Non Operative Treatment on the Chest Wall Deformities

PECTUS
Start date: January 12, 2015
Phase: N/A
Study type: Interventional

The physiological assessment in non-operative treatment on chest wall deformities, are still unclear today. These functional benefits outweigh the aesthetic benefits associated with anatomical improvement. The functional benefits, ventilation, hemodynamic and neurologic, have never been evaluated. Assessment of Effects on parasympathetic activity of the autonomic nervous system, global health criterion measured by noninvasive methods. Anatomic evaluation, between the initial and final assessment by objective measures 1) of the chest wall by MRI, and 2) of the heart by echocardiography. Noninvasive physiological assessment at rest and during exercise in respiratory function exploration flows and volumes, cardiac function by flow measurement, and overall metabolic function test effort (VO2max). Subjective assessment of functional gain between the initial and final balance sheet, based on EVA scales, valued by patients, parents and doctors.

NCT ID: NCT02376634 Withdrawn - Scoliosis Clinical Trials

Hypnotherapy in Major Surgical Procedures

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this randomized controlled study is to test the feasibility of clinical hypnotherapy as a perioperative intervention for the reduction of pre-operative anxiety, post-operative pain, and other-related symptoms (nausea, vomiting, spasms, length of stay, self mastery) in children undergoing scoliosis repair or Nuss procedure.

NCT ID: NCT02337621 Completed - Pectus Excavatum Clinical Trials

Pain, Exercise and Psychological Well-being in Pectus Excavatum

PEP
Start date: May 2015
Phase:
Study type: Observational

Recovery following major surgical procedures can be influenced by both physical (optimization of cardiopulmonary function, pain control, activity) and psychological factors. Physical activity recommendations for post-operative patients is difficult, in part because little is known about the short- and long-term benefits of exercise and mobility on post-operative pain and return to normal functioning.