Patients With SAT or LT After Stent Implantation (PCI) Clinical Trial
Official title:
Molecular and Cellular Mechanisms of the In-stent-thrombosis. Is it Possible to Predict a In-stent-thrombosis Using Biomarkers?
In-Stent-Thrombosis is a rare but serious complication after implantation of stents during PTCA.
In this prospective, open, not-randomized, controlled single-center pilot study 80 patients
having had an in-stent-thrombosis (40 sub-acute thromboses (SAT), 40 late thromboses (LT))
and a control group of 80 patients having not developed a thrombosis will be compared.
The aim of this study is the establishment of diagnostic markers vor prediction of SAT
(detection of CD39- and CD73-activity, respectively)and of LT (EPC-number and function,
respectively) correspondingly aiming at the early identification of patients with high risk
for developing an in-stent-thrombosis.
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Observational Model: Cohort, Time Perspective: Prospective