Patients Undergoing Elective Craniotomy Clinical Trial
Official title:
Conversion From Total Intravenous Anesthesia Technique to Desflurane Anesthesia for Long Duration Neurosurgery: A Pilot Study for Assessment of Recovery Parameters
Since neurological testing during neurosurgery, such as somato-sensory evoked potentials,
motor-evoked potentials, auditory evoked potentials and visual evoked potentials are well
maintained their wave-form reactivity with total intravenous anaesthesia technique better
than inhalational anesthetic techniques, the standard anesthesia method for neurosurgery is
usually total intravenous anaesthesia technique. Nonetheless, after finishing recording the
evoked potential responses during surgery, facilitation of recovery from general anesthesia
is getting important, because the real neurological physical examination is much more
sensitive than above electrical evoked potentials to evaluate the results of surgical
operation.
We propose to evaluate the recovery parameters after conversion from total intravenous
anaesthesia technique to Desflurane anesthesia during long term neurosurgery procedures. The
conversion will be initiated upon completion of the neurophysiological electric evoked
potentials assessment. Based on the pharmacological properties of desflurane, we hypothesize
that recovery after conversion to Desflurane will be faster compared to recovery after total
intravenous anaesthesia alone.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06031883 -
Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia
|
Phase 1/Phase 2 |