Patient Specific Computational Modeling Clinical Trial
Official title:
Development of Parametric Musculoskeletal Models to Investigate the Anatomy and the Function of the PIP
The proximal interphalangeal (PIP) joint is the second joint in the finger from the finger
tip. The outcome following replacement surgery of this joint is considered unsatisfactory. In
order to improve these outcomes, it would be helpful to understand the geometry of the joint,
how it moves and the forces that are involved. This can be achieved using computer models
that model the bones and the soft tissues - musculoskeletal models. In order to make these
models as representative as possible, they should be generated using anatomical data.
Data will initially be extracted from patients' existing magnetic resonance imaging (MRI) and
computed tomography (CT) scans. This will enable the computer model to begin being
constructed. In parallel to the model initialisation, anatomical and motion data of the PIP
joint of healthy volunteers will be collected. The necessary data will be collected using CT
and MRI scans, as well as optical motion tracking methods. These data will then be used to
populate the musculoskeletal model.
Once the model is constructed, it will be used to simulate the motion of the joint and look
at the effect of a simulated PIP joint replacement. This information should then provide
insight as to how PIP joint replacements might be improved in future.
n/a