Clinical Trials Logo

Clinical Trial Summary

Isolated hypoganglionosis is rare and constitutes 3-5% of all congenital neurological bowel diseases. Since hypoganglionosis is associated with symptoms such as chronic constipation or pseudo-obstruction, it can be confused with Hirschprung's disease and it is important to make a differential diagnosis before treatment. Our aim in this study; In addition to sharing the rarely isolated hypoganglionosis and sigmoid volvulus in a 45-year-old male patient with mental retardation, the investigators present a systematic comprehensive review of hypoganglionosis.


Clinical Trial Description

Isolated hypoganglionosis is rare and constitutes 3-5% of all congenital neurological bowel diseases. Since hypoganglionosis is associated with symptoms such as chronic constipation or pseudo-obstruction, it can be confused with Hirschprung's disease and it is important to make a differential diagnosis before treatment. Our aim in this study; In addition to sharing the rarely isolated hypoganglionosis and sigmoid volvulus in a 45-year-old male patient with mental retardation, the investigators present a systematic comprehensive review of hypoganglionosis. Pubmed and Scopus databases were scanned. No restrictions were used in the written language. Only isolated cases of hypoganglionosis were added to the study. In the cases; author, year of publication, country of publication, age, gender, surgical or non-surgical treatments, treatment results, and mortalities were examined.

When sigmoid volvulus is seen in children and adolescents, congenital neurological bowel diseases should be considered in the differential diagnosis. Hirschprung's disease must be ruled out by rectal biopsy. The histopathological investigation should be carried out for the diagnosis and determination of surgical margins in isolated hypoganglionosis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04363125
Study type Observational
Source Dr. Ersin Arslan Education and Training Hospital
Contact
Status Completed
Phase
Start date January 1, 2019
Completion date April 20, 2020

See also
  Status Clinical Trial Phase
Recruiting NCT06035250 - AI Prediction of Gastric Cancer Response to Neoadjuvant Chemotherapy
Not yet recruiting NCT04788927 - Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Not yet recruiting NCT05565677 - Prognostic Value of Lung Cancer MicroAnatomy in 3D
Recruiting NCT05191433 - Effects of Mechanical Ventilation on the Diaphragm in COVID-19 Intensive Care Patients. A Post-mortem Pathology Study
Recruiting NCT04809025 - Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer
Recruiting NCT05218460 - Evaluation of Methodological and Technical DEvelopmeNts to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam on Voluntary Subjects N/A
Recruiting NCT02436122 - Impact of Preoperative HbA1c Levels on Pathologic Features and Oncological Outcomes in the Patients With Prostate Cancer N/A
Not yet recruiting NCT01569542 - Crossed Leg Sign and it's Correlation With Significant Pathology N/A
Not yet recruiting NCT01569555 - Significant Pathology Associated With Crossed Leg Sign N/A
Active, not recruiting NCT01993199 - Deep Biopsy Via Endoscopic Submucosal Dissection in Upper GI Subepithelial Tumors N/A
Recruiting NCT04879056 - Instrument Precision Study for Validation of PIPS 5.1
Completed NCT03986268 - Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy N/A
Completed NCT05983003 - Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data
Completed NCT03991468 - Primary Diagnosis Study for Validation of Hamamatsu NanoZoomer S360MD Digital Slide Scanner System N/A
Completed NCT04356768 - Histological Analysis of Sacrococcygeal Pilonidal Sinus Specimens
Recruiting NCT03230994 - Cooperative Adenomyosis Network
Completed NCT01628250 - Laparoscopic Complete Mesocolic Excision on Colon Cancer N/A
Completed NCT03992768 - Feature Detection Study for Validation of Hamamatsu NanoZoomer S360MD Digital Slide Scanner System N/A
Not yet recruiting NCT04956601 - Adjuvant Radiotherapy in Patients With Early Endometrial Cancer N/A
Completed NCT02971072 - Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy N/A