Early Intervention for Adolescents With Patellofemoral Pain Syndrome

Status Completed

Clinical Trial Summary

Self-reported, unspecific knee pain is highly prevalent among adolescents. A large proportion of the unspecific knee pain can be attributed to Patellofemoral Pain Syndrome (PFPS). There are a number of treatment options for PFPS. Physical therapy has been advocated as one of the cornerstones in rehabilitation of patients with PFPS. Twenty-five years ago, McConnell proposed a multimodal approach that combined several treatment options. The regimen included retraining of the vastus medialis oblique muscle through functional weight bearing activities. This exercise is combined with patellar taping, patellar mobilization, and stretching to improve patellar tracking, reduce pain, and enhance vastus medialis oblique muscle activation. Short term results (<12 months) indicates that multimodal physiotherapy is more effective than placebo treatment.

While treatment for PFPS may be successful for the short-term, long-term results are less promising. A recent review covering the long term prognosis for patients diagnosed with PFPS, reported that only 1/3 of those diagnosed with PFPS and treated conservatively were pain free 12 months after diagnosis. Further ¼ stopped participating in sports because of knee pain.

Predictors of long term outcome (>52weeks) indicate that a long symptom duration, higher age and greater severity at baseline are associated to poorer outcome after treatment. These prognostic factors suggest that an early initiation of treatment might lead to a better long-term prognosis. The purpose of this study is to examine the short and long-term effectiveness of multi-modal physiotherapy compared to standard wait-and-see treatment applied at a very early state of disease among adolescents. The investigators hypothesized a significantly larger proportion of completely recovered patients at three-month follow-up in the interventions group compared to the control group.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01438762
Study type	Interventional
Source	Northern Orthopaedic Division, Denmark
Contact
Status	Completed
Phase	N/A
Start date	June 2011
Completion date	February 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04538508` - Radiofrecuency and Supervised Exercise Versus Supervised Exercise in the Treatment of Patellofemoral Pain Syndrome.	N/A
Completed	`NCT03685812` - Validity and Reliability of Autocad Software Assessment of JPS in PFPS
Completed	`NCT02873143` - 5 Year Follow-up of Adolescents With Knee Pain	N/A
Active, not recruiting	`NCT02114294` - Hip Strengthening Versus Quadriceps Based Training for Patellofemoral Pain Syndrome	N/A
Completed	`NCT02243332` - Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain	N/A
Completed	`NCT01696162` - Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain	N/A
Completed	`NCT01434966` - Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain	N/A
Not yet recruiting	`NCT05327569` - The Efficacy of Myofascial Chain Release Techniques in Patients With Patellofemoral Pain Syndrome.	N/A
Completed	`NCT06060730` - Measurement Properties of the Turkish Version of the Patellofemoral Pain and Osteoarthritis Subscale of the KOOS
Completed	`NCT03281421` - Immediate Effects of Ankle Mobilization on Dorsiflexion Range of Motion in Women With Patellofemoral Pain.	N/A
Recruiting	`NCT06130696` - Clamshell Exercise in Patellofemoral Syndrome.	N/A
Completed	`NCT03201133` - Clinical Subgroups in Patellofemoral Pain Syndrome
Completed	`NCT05959148` - Adjuvant Effects of Monochromatic Infrared Energy in Rehabilitation of Adolescents With Patellofemoral Pain Syndrome	N/A
Completed	`NCT02646579` - Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only	N/A
Completed	`NCT00978003` - Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteer
Not yet recruiting	`NCT04631614` - Addition Effect of the Ankle Manual Therapy to Muscle Strengthening Exercise in Women With Patellofemoral Pain	N/A
Not yet recruiting	`NCT05383781` - Effect of Short Foot Exercise in Treatment of Patients With Patellofemoral Pain Syndrome	N/A
Not yet recruiting	`NCT05083897` - Effect of Hip Adductors Isometric Contraction on Knee Extensors Isokinetic Torque in Patellofemoral Pain Syndrome
Withdrawn	`NCT03157271` - The Addition of Dry Needling in the Treatment of Patients With Patellofemoral Pain Syndrome	N/A
Enrolling by invitation	`NCT02548988` - Selective Neuromuscular Electrical Stimulation on VMO	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.