Study of VX-765 in Subjects With Treatment-resistant Partial Epilepsy

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the safety, tolerability, and efficacy of VX-765 in subjects with Treatment-resistant Partial Epilepsy

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01048255
Study type	Interventional
Source	Vertex Pharmaceuticals Incorporated
Contact
Status	Completed
Phase	Phase 2
Start date	January 2010
Completion date	November 2010

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT00982787` - Safety and Anticonvulsant Efficacy of Passiflora Incarnata Extract in Patients With Partial Epilepsy	Phase 2
Completed	`NCT00898560` - Effect of Repeat Administration of Eslicarbazepine Acetate on the Pharmacokinetics of a Combined Oral Contraceptive	Phase 1
Recruiting	`NCT01735032` - Multimodal Imaging in Pre-surgical Evaluation of Epilepsy	N/A
Completed	`NCT01090934` - Localizing the Epileptogenic Zone With High Resolution Electroencephalography	N/A
Terminated	`NCT00391534` - EXTENT: EXtended Tolerability and Efficacy of a Novel Formulation of Oxcarbazepine in a Trial in Partial Epilepsy	Phase 3
Terminated	`NCT01496612` - Buspirone Therapy for Localized Epilepsy	Phase 2
Completed	`NCT00900237` - Study to Evaluate Pharmacokinetics and Tolerability of Multiple Doses of Eslicarbazepine Acetate and Oxcarbazepine	Phase 1
Recruiting	`NCT04903314` - Dose-Escalation Study of Cenobamate (YKP3089) in Pediatric Subjects With Partial-Onset Seizures	Phase 1
Completed	`NCT01373190` - Thermographic Examination of Skin Temperatures in Individuals With Focal Onset Epilepsy	N/A
Completed	`NCT00894478` - Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging	N/A
Recruiting	`NCT03478852` - Investigating Epilepsy: Screening and Evaluation
Recruiting	`NCT01273129` - Surgery as a Treatment for Medically Intractable Epilepsy
Completed	`NCT00001666` - Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy	N/A
Completed	`NCT00001932` - Serotonin Receptors in Seizure Disorders	N/A
Completed	`NCT00908349` - Safety and Tolerability of OXC XR as Adjunctive Therapy in Subjects With Refractory Partial Epilepsy	Phase 3
Completed	`NCT02076698` - Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Epilepsy	Phase 3
Completed	`NCT00706160` - Language Mapping in Patients With Epilepsy
Completed	`NCT01397968` - Efficacy and Safety of YKP3089 in Subjects With Treatment Resistant Partial Onset Seizures	Phase 2
Completed	`NCT01866111` - A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures	Phase 2
Completed	`NCT00957047` - Efficacy and Safety Study of BIA 2-093 in Combination With Other Anti-Epileptic Drugs to Treat Partial Epilepsy	Phase 3