Parkinson Clinical Trial
— AOT-PAOfficial title:
Action Observation Treatment and Motor Imagery as Rehabilitation Tools in Parkinson's Disease Patients
NCT number | NCT04181918 |
Other study ID # | AOTPRFDG |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | March 26, 2018 |
Est. completion date | June 26, 2020 |
The aim of the study is to assess the role of Action Observation Treatment (AOT) and Motor Imagery (MI) in the rehabilitation of Parkinson's disease patients, as compared to a control condition. Main outcome measures will be the results in two functional scales (FIM, UPDRS) and kinematics parameters obtained from gait analysis. Data at two months and six months follow up, respectively, will be also collected.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | June 26, 2020 |
Est. primary completion date | March 26, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Parkinson disease patients on Hoehn and Yahr 3-4 Exclusion Criteria: - Mini-Mental State Examination < 24 - Fluent aphasic patients - Apraxia - Neglect - major neuropsychiatric disorders |
Country | Name | City | State |
---|---|---|---|
Italy | Fondazione Don Carlo Gnocchi | Parma |
Lead Sponsor | Collaborator |
---|---|
Fondazione Don Carlo Gnocchi Onlus |
Italy,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | change in the functional status of the patient | to assess the change in the functional status of the patient, the Functional Independence Measure (FIM) will be used. FIM consists in a 7-point scale (1 = <25% independence; total assistance required, 7 = 100% independence), and it can detect changes in the patient's status in 18 categories, focusing on motor and cognitive function. Functional patients' status will assess before treatment, within one week after the end of the treatment (after treatment) and two months' follow up. | Before treatment, within one week after treatment, two months' follow up | |
Primary | change in Parkinson disease motor symptoms | to assess the change in motor status of the patient, the Unified Parkinson's Disease Rating Scale (UPDRS) will be used, and it consists in a 5-point scale (0 = no signs; 4 = severe). UPDRS will be administered before treatment, within one week after the end of the treatment (after treatment) and two months' follow up. | Before treatment, within one week after treatment, two months' follow up | |
Primary | change in kinematic parameters of the gait (velocity, footing, pace, step length) | to assess the change of patient's gait parameters, the kinematic analysis will be used (i.e. gait analysis). The gait analysis allows to detect fine-grain changes in kinematic parameters of the movement, through a non-invasive methodology. Gait analysis will be performed before treatment, within one week after the end of the treatment (after treatment) and two months' follow up. | Before treatment, within one week after treatment, two months' follow up |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT06037590 -
A Pilot Comparative Bioavailability Study of Levodopa Administered Via Levodopa Cyclops™ Relative to INBRIJA®
|
Phase 1 | |
Recruiting |
NCT01537224 -
Electrophysiological Activity of the Subthalamic Nucleus During the Processing of Emotional and Motivational Information
|
N/A | |
Withdrawn |
NCT04011449 -
State-dependent Pathophysiological Oscillations in Parkinson's Disease and Treatment With DBS Using the Medtronic RC+S
|
N/A | |
Completed |
NCT02539446 -
Suprapostural Attention Focus and Postural Difficulty on H-reflex and Brain Activity: Aging and Parkinson's Disease
|
N/A | |
Completed |
NCT00358189 -
Effects of Deep Brain Stimulation for the Treatment of Parkinson's Disease
|
N/A | |
Active, not recruiting |
NCT04606979 -
tDCS of the Primary Motor Cortex to Improve Implicit Motor Sequence Learning in Parkinson's Disease
|
N/A | |
Completed |
NCT05119803 -
The Relationship of Spine Posture and Mobility With Upper Extremity Functions in Parkinson's Patients
|
||
Recruiting |
NCT06154772 -
Quality of Life, Anxiety and Fatigue Level of Parkison's Patients With Color Therapy
|
N/A | |
Not yet recruiting |
NCT02249715 -
Development of a Monitoring Set-up and Algorithm Using Functional MRI (fMRI) and EEG for Prediction of Response to Repetitive Deep Transcranial Magnetic Stimulation (rDTMS) for Patients With Parkinson's Disease
|
N/A | |
Completed |
NCT01732653 -
A Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults
|
N/A | |
Completed |
NCT03232996 -
Evaluation of a Computer Game Based Rehabilitation System for Assessment and Treatment of Balance and Gait Impairments in Individuals With Parkinson's Disease.
|
N/A | |
Enrolling by invitation |
NCT04566341 -
Study of Gastrointestinal Dysfunction and Enteric Neural Pathology in Patients With Parkinson's Disease
|
||
Active, not recruiting |
NCT04978597 -
Early ParkinSon wIth L-DOPA/DDCI and OpicapoNe (EPSILON Study)
|
Phase 3 | |
Recruiting |
NCT06116084 -
Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine
|
N/A | |
Recruiting |
NCT05830396 -
GRoningen Early-PD Ambroxol Treatment
|
Phase 2/Phase 3 | |
Not yet recruiting |
NCT05379062 -
Choral Singing for Patients With Parkinson's
|
N/A | |
Completed |
NCT02071823 -
Comparative Bioavailability Study of BIA 9-1067 25 mg Capsules
|
Phase 1 | |
Recruiting |
NCT03558568 -
The Effect of Deep Brain Stimulation on Facial Expressions.
|
N/A | |
Enrolling by invitation |
NCT05596201 -
Super-resolution of Brain Magnetic Resonance Images in Deep Brain Stimulation for Parkinson's Disease
|
||
Completed |
NCT02305277 -
Relative Bioavailability and Bioequivalence Of Different Formulations of Opicapone in Healthy Volunteers
|
Phase 1 |