Parkinson Clinical Trial
Official title:
Investigation of the Efficacy and Safety of IncobotulinumtoxinA (Xeomin) in Parkinson's Disease Tremor: A Customized Approach
The scientific aim of this study is to investigate the efficacy and safety of incobotulinumtoxinA (Xeomin-Merz Pharmaceuticals) in the tremor of Parkinson‟s disease. Our hypothesis is that injection of Xeomin into the muscles of arm, forearm and hand decreases the tremor amplitude and frequency leading to improvement of the patient‟s function.
This is an investigator initiated, randomized, double blind, placebo controlled, cross over
study which is supported by Merz pharmaceuticals. Patients with Parkinson‟s disease (at Yale
Neurology and Movement disorders clinics) will be approached by the members of the research
team (PI and sub-investigators) to see if they meet inclusion and exclusion criteria and
wish to participate in the study.
If eligible and consented to participate in the study, there will be a series of
questionaires, examinations and treatment sessions.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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