Clinical Trials Logo

Clinical Trial Summary

Anosognosia is a recognised condition for people with Parkinson's, and is the result of physiological damage on brain structure.

Surgical Parkinson Disease Nurse Specialists have noticed that when reviewing the pre-surgery videos 12 months post-DBS, patients have forgotten and are shocked at how bad their symptoms were prior to surgery (personal communication), which may not be reflected in the change in QoL reported.

This lack of awareness, while possibly helpful in everyday life, may lead to effective treatments looking ineffective, or the benefits in QoL of effective treatment appearing reduced. This confound may not only reduce the apparent effectiveness but also the related cost-effectiveness of treatment. As cost-effectiveness is determined by both size and longevity of an effect, current methods of capturing these data may be suboptimal.


Clinical Trial Description

The overarching aim of this project is to identify coping mechanisms and pathological lack of self-awareness and the impact they are likely to have on patient reported quality of life (QoL) outcome measures for a chronic condition.

This will be an observational study, a case series of approx. 10 to 20 patients. These patients will be recruited over a 6 month period from the Queen Elizabeth Hospital, Birmingham and will be informed of the study during their routine pre-surgical visit.

Patients will be eligible if they are about to undergo DBS at Queen Elizabeth Hospital. If the participant has a carer, who is also willing to participate, they may also join the study. Patients will be excluded if they are unable to complete questionnaires in English.

Once recruited and following consent, a patient will complete a brief battery of questionnaires both self-reported and clinician rated prior to surgery and at their 6 month post op visit. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02561715
Study type Observational
Source University of Birmingham
Contact
Status Withdrawn
Phase
Start date August 1, 2015
Completion date July 18, 2019

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT01467960 - Apolipoprotein D (ApoD) In Human Serum As Marker Of Parkinson's Disease N/A
Recruiting NCT05516719 - Longitudinal Investigation of I2BS in PD
Enrolling by invitation NCT02670161 - Quality Improvement and Practice Based Research in Neurology Using the EMR Phase 4
Recruiting NCT05518617 - Molecular and Functional Imaging in Monogenic PD.
Recruiting NCT05516732 - Serotonin Release in Premotor and Motor PD
Terminated NCT02315781 - tDCS in Parkinson's Disease With Depression N/A
Recruiting NCT06036433 - Light Therapy Plus Exercise to Improve Motor, Non-Motor Symptoms and QoL in Parkinson's Disease N/A
Completed NCT02271685 - Sound Estimation and Accuracy Task N/A
Withdrawn NCT02177149 - Nurse Management of Neuromodulation Therapy N/A
Completed NCT02468804 - Cognitive Dysfunction In Parkinson's N/A