Effect of Deep Brain Stimulation on Neuropsychiatric Fluctuations in Patients With Parkinson's Disease — PSYCHOSTIM

Parkinson's Disease (Disorder) Clinical Trial

Official title:
Effect of Bilateral Subthalamic Nucleus Deep Brain Stimulation on Neuropsychiatric Fluctuations in Patients With Parkinson's Disease, Evaluated With a New, Dedicated Scale

Status Completed

Clinical Trial Summary

Retrospective, monocentric, observational study designed to evaluate the effects of Bilateral Subthalamic Nucleus Deep Brain Stimulation (DBS STN) on Neuropsychiatric fluctuations in Patients with Parkinson's Disease (PD)

Clinical Trial Description

Pre-operative versus 12-Month Follow-Up analysis of changing in Neuropsychiatric Fluctuations Scale (NFS) score in preoperative versus postoperative MED OFF (during acute withdrawal of dopaminergic therapy) and MED ON (during super-liminal Levodopa dose) conditions. Postoperative evaluations are always performed with DBS turned on and stimulating (STIM ON) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04608123
Study type	Observational
Source	University Hospital, Grenoble
Contact
Status	Completed
Phase
Start date	May 1, 2020
Completion date	July 21, 2020

View Details

See also
	Status	Clinical Trial	Phase
	Completed	`NCT03670953` - A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Participants With Motor Fluctuations	Phase 3