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Parasomnias clinical trials

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NCT ID: NCT03478306 Completed - Clinical trials for Diabetic Retinopathy

Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm

Start date: March 27, 2018
Phase: Phase 3
Study type: Interventional

This study evaluates the effect of melatonin 4 mg on circadian rhythm and visual function of patients with diabetes mellitus. Half of the patients will receive melatonin (arm-1) and the other half will receive placebo (arm-2), both groups in 3 weeks. After a week of washout, the patients will cross over to the other treatment arm.

NCT ID: NCT03468400 Completed - Insomnia Clinical Trials

Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire

Start date: March 1, 2018
Phase:
Study type: Observational

The study aims to develop and test a user-friendly, accessible approach to sleep assessment which can function as an initial "triage" of targeted sleep conditions, such as insomnia, insufficient sleep syndrome, sleep apnea syndromes/snoring, and circadian sleep/wake disorders, within the clinical and community population. Specifically, this study will test the validity and reliability of a self-rated, digitized, and cost-effective diagnostic measure with sufficient sensitivity to accurately assess/diagnose common sleep conditions and/or risk for these conditions. Such an approach, would allow for faster assessment of common sleep conditions and disorders, and provide clinical knowledge to the individual, the physician, and if required insurance companies, as to those persons who need more immediate attention or treatment for their sleep condition.

NCT ID: NCT03456219 Completed - Clinical trials for Shift Work Type Circadian Rhythm Sleep Disorder

Determination of Protocol of Nocturnal Food Intake of Shift Workers.

Start date: June 27, 2017
Phase: N/A
Study type: Interventional

This study evaluates the effect of different dietary conducts in the nocturnal period on the postprandial metabolism and food perceptions of night workers of the Hospital of Clinics of Uberlândia, Federal University of Uberlândia.

NCT ID: NCT03445351 Completed - Lipodystrophy Clinical Trials

Quality of Life, Sleep, and Biomarkers in People With HIV/AIDS

PLHA
Start date: January 20, 2013
Phase: N/A
Study type: Interventional

Aim: Evaluate the influence of exercise, in different times, on quality of life, sleep and clinical parameters in people living with HIV/AIDS (PLHA). Methods: Intervention study, prospective.

NCT ID: NCT03415230 Completed - Anxiety Clinical Trials

Effect of Therapeutic Massage on Sleep Quality and Stress Levels in Women With Breast Cancer

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

This is a randomized control trial to test the effectiveness of therapeutic massage on the sleep quality and the stress levels in women that have completed their treatment for breast cancer.

NCT ID: NCT03412591 Completed - Sleep Disturbance Clinical Trials

The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial

Suvsubuse
Start date: July 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Insomnia is an extremely common and poorly treated problem in patients with substance use disorders (SUD)s undergoing rehabilitation treatment in a residential facility. The persistence of insomnia in substance use disorders (SUDs) may be associated with tonic levels of drug craving. Insomnia and craving can predispose to relapse in patients with SUDs. Insomnia and SUDs are independently associated with increased cortisol indicating physiological dysregulation of the stress response system including the hypothalamic-pituitary-adrenal (HPA) axis. Hence sleep disturbance, craving and increased cortisol leads to relapse in SUD subjects. Suvorexant, an orexin 1 / 2 receptor antagonist, approved by the FDA for the treatment of sleep disturbance in subjects with primary Insomnia. Previous animal studies report Orexin 1 receptor antagonist decreases craving and normal the HPA axis. However, the efficacy of suvorexant on sleep and craving in SUD subjects is not known. The primary aims of this study are- 1. To determine if suvorexant will improve sleep quality (increased total sleep time, fewer awakenings), as measured through wrist actigraphy and the Insomnia Severity Index (ISI) in SUDs. 2. To assess whether or not SUDs patients treated with suvorexant endorse scale items on a modified abuse liability assessment battery. 3. To determine if daily reports of mood, stress, craving and sleep using Ecological Momentary Assessment (EMA data) change during the course of the study as patients with SUDs are treated with suvorexant. 4. To determine if patients taking suvorexant will have a decrease in total daily salivary cortisol over the course of the study by collecting samples at five time points in a day, for two consecutive days at two different times in the study.

NCT ID: NCT03380897 Completed - Depression Clinical Trials

Sleep and Depression in Induction of Labour

Start date: June 7, 2017
Phase: N/A
Study type: Interventional

Randomised trial comparing double balloon catheter for induction of labor between inpatient and outpatient groups. The investigators assess how sleep disturbances and depression of the mother affect to the pain during balloon catheter induction of labour.

NCT ID: NCT03370354 Not yet recruiting - Clinical trials for Sleep Disorders, Circadian Rhythm

Nursing Activity and Quality of Hospitalized Patients' Sleep

SOMACTIV
Start date: February 1, 2018
Phase: N/A
Study type: Observational

This study is to determine the impact of night shift nurse's activity on patients' sleeping patterns in medical services including individual, clinical and environmental factors. The patients will be questioned in order to create both a control group and a group with troubled sleeping patterns.

NCT ID: NCT03353558 Not yet recruiting - Sleep Disorder Clinical Trials

Sleep Assessment in CML

CML-SLEEP
Start date: December 2017
Phase: N/A
Study type: Observational

Patients with CML report on fatigue, and many of them report on sleep disturbances. The investigators wish to objectively assess the patient's sleep using a sleep "wrist watch" (Actigraph) , and correlate data with their perception of sleep quality. A matched participants group will serve as control. the Control group is defined as participants not having CML or any other malignancy and without any known sleep disturbances.

NCT ID: NCT03339258 Active, not recruiting - Clinical trials for Stress Disorders, Post-Traumatic

A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD

Start date: April 15, 2018
Phase: Phase 2
Study type: Interventional

This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full and partial-syndromal PTSD.