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Parasomnias clinical trials

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NCT ID: NCT05252598 Withdrawn - Anxiety Clinical Trials

Mood and Cognitive Effects of Psilocybin in Healthy Participants

MELO
Start date: January 2023
Phase: Early Phase 1
Study type: Interventional

This study is seeking to find the optimal microdose or low dose of psilocybin (magic mushrooms) that provides general enhancements to mood, memory, sleep, and other measures of general well-being without any hallucinogenic effects.

NCT ID: NCT05097651 Withdrawn - Sleep Disturbance Clinical Trials

CBD for Sleep in People With HIV

Start date: April 1, 2021
Phase: Phase 2
Study type: Interventional

This study will obtain preliminary information about whether, and at what dose, cannabidiol (CBD) may help with insomnia in people living with human immunodeficiency virus (HIV). The study will be a 5-week randomized, double-blind placebo-controlled phase II trial using daily oral CBD doses between 50mg and 600mg. Sleep problems will be measured using a wrist-worn device and by self-report. Performance on tests of thinking skills will be compared before and after CBD/placebo treatment. Positive study results will provide support for the use of CBD as a potential treatment for insomnia.

NCT ID: NCT04780893 Withdrawn - Insomnia Clinical Trials

Electrical Vestibular Nerve Stimulation (VeNS) as a Method of Sleep Management in People With PTSD

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

This double blind randomized controlled study will enroll 20 subjects and will be conducted remotely. The study will be randomized for an 8-week period with a 1:1 active to sham device allocation. Primary endpoint analysis will be performed at 4 weeks.

NCT ID: NCT04506112 Withdrawn - Sleep Disturbance Clinical Trials

Optimizing Cardiac Rehabilitation by Integrating Sleep Therapeutics

Start date: January 27, 2022
Phase: N/A
Study type: Interventional

The study aims are to: 1) optimize the Transdiagnostic Sleep and Circadian Intervention (TranS-C) for delivery to Veterans in cardiac rehabilitation, 2) test and refine the adapted TranS-C treatment manual and protocol, and 3) conduct a pilot randomized trial to establish the feasibility, acceptability, and plausibility of the intervention protocol and study procedures.

NCT ID: NCT04236661 Withdrawn - Sleep Disturbance Clinical Trials

Reports on Sleep Quality and Thermoregulation Among Veterans

ReSQuTheVets
Start date: July 2020
Phase: N/A
Study type: Interventional

To assess and compare the quality of sleep self- reported by veterans with sleep disorders before and after use of the Chilipad cooling mattress pad

NCT ID: NCT02906904 Withdrawn - Sleepwalking Clinical Trials

Pain Sensitivity in NREM Parasomnia (NOCISOMNIE)

NOCISOMNIE
Start date: October 2015
Phase: N/A
Study type: Interventional

Non Rapid Eye Movement (NREM) sleep parasomnias (sleepwalking and sleep terrors) are frequent and disabling sleep disorders characterized by arousal specifically from slow wave sleep (SWS) with dissociated brain activity that may be related to lower nociceptive state. The investigators recently reported frequent subjective complaints of chronic pain, migraine and headache during wakefulness in adult sleepwalkers. They also described frequent analgesia during severe and injuring episodes, suggesting a relationship between dissociated brain activity and nociceptive dysregulation. However, this study did not included objective nociceptive measures and the retrospective assessment of perceived pain during parasomnia episodes over a lifetime span might also introduce a recall bias. The aims of the present study are to measure objective pain sensitivity in patients with NREM parasomnias and matched controls during 1) parasomniac episodes, 2) light NREM sleep and SWS, and 3) wakefulness. Fifteen adults with severe NREM parasomnia and 15 age and sex-matched controls will be recruited. A 25 hours (8 AM to 9 AM) sleep deprivation protocol followed by auditory stimulations during SWS will be used to trigger parasomniac episodes. Thermoalgic stimulations of graduate intensity will be applied during wakefulness (8 PM) to determine the nociceptive threshold. During the recovery sleep following the sleep deprivation, the investigators will apply repeated subthreshold thermoalgic stimulations in NREM stage 2, SWS and triggered parasomniac episodes and report the behavioural/neurophysiologic nociceptive responses. The investigators hypothesized a lower nociceptive threshold during wakefulness in sleepwalkers and a decrease of the arousabiliy during SWS and parasomniac episodes. This study may help to better understand the etiology and mechanisms underlying the clinical enigma of the nociceptive dysregulation in NREM sleep parasomnias.

NCT ID: NCT02593981 Withdrawn - Sleep Clinical Trials

Addressing Sleep Problems in Older Adults

Start date: March 2018
Phase: N/A
Study type: Interventional

As many as 57% of older adults complain of major disruption of sleep, 29% struggle to fall asleep and 19% complain of early-morning awakening. The implications of this sleep deprivation are sobering, particularly among older individuals. The primary goal of this study is to determine whether a palatable foodstuff which contains a fruit/honey drink and which is taken every evening before bedtime leads to improved sleep in community-living individuals with sleep problems.

NCT ID: NCT02390583 Withdrawn - Internet Addiction Clinical Trials

Internet Addiction and Sleep Disorders

ADDICSOM
Start date: September 2016
Phase: N/A
Study type: Interventional

This is an open label randomized controlled trial, comparing two modes of treatment for internet addiction (gaming or gambling online) with sleep disorders associated.

NCT ID: NCT02109237 Withdrawn - Clinical trials for Bronchiolitis Obliterans

Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3

Start date: May 2014
Phase: N/A
Study type: Interventional

This study is to determine whether sleep disorders contribute to impaired quality of life and mobility in patients with Bronchiolitis Obliterans syndrome and whether non invasive positive airways pressure ventilation can improve sleep, quality of life and mobility in this patient group.

NCT ID: NCT01978340 Withdrawn - Clinical trials for Sleep Apnea, Obstructive

Eval EarlySense Bet Lowenstein Sleeplab

Start date: November 2013
Phase: N/A
Study type: Observational [Patient Registry]

The study objective is to collect heart rate, respiration rate and motion data of patients admitted to sleep lab and to determine the accuracy level of the EarlySense system vs. the monitors used in sleep lab (e.g., Polysomnography, respiratory belts, ECG, etc..) . Data regarding sleep condition, scoring and quality of sleep and in and out of bed status, patient turns will also be collected and compared to data collected by EarlySense contactless monitor. Different patient population will be monitored including obese, morbidly obese, patients with or without obstructive/central apnea, patients with or without arrhythmia as well as healthy population who arrive to sleep lab for general evaluation will be monitored