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Papillomavirus Infections clinical trials

View clinical trials related to Papillomavirus Infections.

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NCT ID: NCT06075264 Recruiting - HPV Infection Clinical Trials

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

ART-VIN IIB
Start date: December 6, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II double-blind, placebo-controlled study of artesunate ointment for the treatment of HPV-associated vulvar HSIL (usual type vulvar intraepithelial neoplasia 2/3).

NCT ID: NCT06052033 Recruiting - HPV Infection Clinical Trials

Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection

Start date: September 11, 2023
Phase: N/A
Study type: Interventional

Non-RCT clinical trial comparing 5-ALA photodynamic therapy and CO2 laser for persistent high-risk HPV-related low-grade cervical lesions.

NCT ID: NCT06041061 Active, not recruiting - HPV InfectioN Clinical Trials

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SCT1000 in Healthy Women Aged 18-45 Years

Start date: August 13, 2023
Phase: Phase 3
Study type: Interventional

A total of 18000 healthy women aged 18-45 years old were divided into three age groups: 18-26 years old, 27-35 years old, and 36-45 years old. The experimental group and the placebo group were randomly assigned in a ratio of 1:1. All subjects enrolled in the upper arm deltoid muscle were injected with 3 doses of test vaccine or placebo according to the 0, 2, and 6 months immunization program.

NCT ID: NCT06005389 Completed - Clinical trials for Human Papillomavirus Infection

Serum Galectin-3 as a Marker of Human Papillomavirus Infection

Start date: December 1, 2021
Phase:
Study type: Observational

This study aimed to assess the serum Galectin-3 levels in patients with warts both before and after cryotherapy and to investigate its potential contribution to the pathogenesis of human papillomavirus infection.

NCT ID: NCT06002126 Recruiting - HIV Infections Clinical Trials

Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries

Start date: August 2, 2023
Phase: N/A
Study type: Interventional

Cervical cancer is a relatively common cancer among women living with human immunodeficiency virus (HIV). This study will test women for human papillomavirus (HPV) infection of the cervix. The main purpose of this study is to determine the best way to test for damaged areas of the cervix. Damaged areas of the cervix should be treated and removed to prevent cancer of the cervix. Women in this study will be seen once, twice or three times in a year. Women will provide several samples related to screening for cervical cancer including a swab of the cervix, a self-collected swab of the vagina and urine. Women will have a detailed examination of the cervix called colposcopy and have a few biopsies, or small pinches of the cervix, to look for areas at risk for turning into cancer. If HPV of the cervix is found but treatment of the cervix is not indicated, women will return in 6 months and in 12 months to repeat these tests. Most women will only need 1 visit. Women found to have damaged areas of the cervix at risk for turning into cancer will be referred for treatment. This protocol will compare different tests to understand the best test to identify women at risk for cervical cancer.

NCT ID: NCT06001190 Recruiting - Clinical trials for Probiotic, Human Papillomavirus Infection, Pap Smear, Microbiome

The Influence of Oral Probiotic on the Vaginal Flora and Microenvironment Alteration in the Vaginosis Infection Women

Start date: July 15, 2023
Phase: N/A
Study type: Interventional

A single-blind, randomized, and probiotic-treatment including adult women with vaginitis and/or HPV positive. After oral probiotics, all participants will be followd-up cervical swabs and vaginal microbiome alteration till the end of the study.

NCT ID: NCT06000527 Recruiting - Clinical trials for Juvenile Recurrent Respiratory Papillomatosis

Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

REPA
Start date: October 1, 2022
Phase:
Study type: Observational

Recurrent respiratory papillomatosis (RRP) is a rare disease. However, it is the most common benign laryngeal tumor in children. To date, no epidemiological data are available in France. The aim of this study is to establish the epidemiology of juvenile PPR.

NCT ID: NCT05990270 Recruiting - HPV Infection Clinical Trials

The Effect of Education Given to Women on Cervical Cancer on Knowledge, Attitude and Belief

EEWCCKAB
Start date: August 15, 2023
Phase: N/A
Study type: Interventional

Aim: The aim of this study is to reveal the effect of education given to women about cervical cancer on knowledge, attitude and belief. Material and Method: This randomized controlled study was conducted with 130 who had a public hospital located in Southeast Turkey (51 experimental, 51 control).

NCT ID: NCT05981807 Not yet recruiting - Clinical trials for Sexually Transmitted Diseases

HPV Infection, Sexually Transmitted Infections and Anal Dysplasia in the Transgender Population

PrevHPV-TG
Start date: October 2023
Phase:
Study type: Observational

The goal of this observational study is to estimate the prevalence of HPV infections anal and ENT level and according to HIV status in transgender (TG) population. The main question it aims to answer is: - What is the prevalence of HPV lesions in transgender population (TG); - What kind of high risk HPV (hrHPV) and low risk HPV (lrHPV) are detected at the genital, anal and ENT level

NCT ID: NCT05973487 Recruiting - Ovarian Cancer Clinical Trials

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Start date: May 6, 2024
Phase: Phase 1
Study type: Interventional

TScan Therapeutics is developing cellular therapies across multiple solid tumors in which autologous participant-derived T cells are engineered to express a T cell receptor that recognizes cancer-associated antigens presented on specific Human Leukocyte Antigen (HLA) molecules. This is a multi-center, non-randomized, multi-arm, open-label, basket study evaluating the safety and preliminary efficacy of single and repeat dose regimens of TCR'Ts as monotherapies and as T-Plex combinations after lymphodepleting chemotherapy in participants with locally advanced, metastatic solid tumors disease.